173260-06-5

Usage

Molecular structure

The compound has a pyrazolo-pyridine core structure, which consists of a pyrazole ring fused to a pyridine ring.

Amino group

The compound contains an amino group (-NH2), which can participate in various chemical reactions and can form hydrogen bonds.

Phenyl group

A phenyl group (-C6H5) is attached to the compound, which can influence its stability, solubility, and interactions with other molecules.

Dimethylamino group

The compound features a dimethylamino group (-N(CH3)2), which can contribute to its basic properties and solubility.

Dimethyl ester form

The carboxylic acid groups are in the form of dimethyl esters (-COOCH3), indicating two methyl groups are attached to the carboxylic acid groups.

Potential applications

1H-Pyrazolo[3,4-b]pyridine-5,6-dicarboxylic acid, 4-amino-3-[4-(dimethylamino)phenyl]-1-phenyl-, dimethyl ester may have potential uses in medicinal chemistry, such as in the development of new drugs or as a research tool in biological studies.

Unique structure

The complex structure of the compound suggests it may have interesting properties that could be explored further in various applications.

Upstream product

• 762-42-5 dimethyl acetylenedicarboxylate 
• 173259-95-5 5-amino-3-(4-(dimethylamino)phenyl)-2,3-dihydro-1-phenyl-1H-pyrazole-4-carbonitrile 
• 100-63-0 phenylhydrazine 
• 6673-15-0 2-(4-dimethylaminophenyl)ethylene-1,1,2-tricarbonitrile 

Relevant academic research and scientific papers

Method of quantitative determination of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative

Disclosed is a chemiluminescent method of quantitatively determining one of peroxide, a peroxidation-active substance or a pyrazolopyridopyridazine derivative represented by the formula (I): wherein R1represents hydrogen, lower alkyl, optionally substituted aryl, optionally substituted heterocyclic group, substituted sulfonyl, substituted sulfinyl, substituted thio etc.; R2represents hydrogen, lower alkyl, optionally substituted aryl, etc., or a salt thereof;, characterized by subjecting an unknown amount of one substance selected from the peroxide, peroxidation-active substance and pyrazolopyridopyridazine derivative to react with a known amount of the remaining two substances.

Synthesis and chemiluminescence of 1,3-disubstituted pyrazolo[4',3':5,6]pyrido[2,3-d]pyridazine-5,8(6H,7H)-diones and related compounds

Reactions of 1,3-disubstituted 5-aminopyrazole 5-aminopyrazole-4-carbonitrile derivatives (3a-o) with dimethyl acetylenedicarboxylate in the presence of potassium carbonate in dimethyl sulfoxide gave the corresponding dimethyl 1,3-disubstituted pyrazolo[3,4-b]pyridine-5,6-dicarboxylates (4a-o) which were allowed to react with excess hydrazine hydrate in ethanol under reflux followed by heating at 250-300°C to give 1,3-disubstituted 4-amino-1H-pyrazolo[4',3':5,6]pyrido[2,3-d]pyridazine-5,8(6H,7H)-dione s (7a-s) in good yields. These tricyclic pyridazine derivatives were evaluated for chemiluminescence. Some were found to be more efficient than luminol in light production. 4-Amino-3-methylsulfonyl-1-phenyl-1H-pyrazolo[4',3':5,6]pyrido[2,3-d]p yridazine-5,8(6H,7H)-dione (7r) showed the greatest chemiluminescence intensity derivatives in the presence of H2O2, peroxidase, in a solution of phosphate buffer pH 8.0.