173314-98-2

Usage

Uses

Used in Organic Synthesis:
2-Pyridinamine,6-ethynyl-(9CI) is used as a building block for the synthesis of more complex organic molecules. Its ethynyl group allows for further chemical reactions and modifications, making it a versatile component in the creation of various organic compounds.
Used in Pharmaceutical Research:
2-Pyridinamine,6-ethynyl-(9CI) is used as a precursor for the development of new pharmaceutical compounds. Its unique structure may contribute to the discovery of novel drugs with potential therapeutic applications. Further research and testing are needed to fully understand its potential applications and effects in the pharmaceutical industry.

Upstream product

• 19798-81-3 2-Amino-6-bromopyridine 
• 1066-54-2 trimethylsilylacetylene 
• 173314-97-1 2-amino-6-<(trimethylsilyl)ethynyl>pyridine 

Downstream Products

• 1429913-21-2 6-(1-benzyl-1H-1,2,3-triazol-4-yl)pyridin-2-amine 
• 1398592-34-1 C₄₂H₄₀BrN₇O₂ 
• 1350351-40-4 3-((6-aminopyridin-2-yl)ethynyl)-5-(4-(isopropylsulfonyl)phenyl)pyrazin-2-amine 

Relevant academic research and scientific papers

Multidentate, V-Shaped Pyridine Building Blocks as Tectons for Crystal Engineering

The formation of supramolecular structural units through self-assembly is a powerful method to design new architectures and materials endowed with specific properties. With the aim of adding a group of versatile tectons to the toolkit of crystal engineers, we have devised and synthesised four new V-shaped building blocks characterised by an aryl acetylene scaffold comprising three substituted pyridine rings connected by two triple bonds. The judicious choice of different substituents on the pyridine rings provides these tectons with distinctive steric, electrostatic and self-assembly properties, which influence their crystal structures and their ability to form co-crystals. Co-crystals of the tectons with tetraiododifluorobenzene were obtained both via traditional and mechanochemical crystallisation strategies, proving their potential use in crystal engineering. The energetic contributions of the supramolecular interactions at play in the crystal lattice have also been evaluated to better understand their nature and strength and to rationalise their role in designing molecular crystals.

Harnessing the Dual Properties of Thiol-Grafted Cellulose Paper for Click Reactions: A Powerful Reducing Agent and Adsorbent for Cu

A new approach exploiting the dual properties of thiol-grafted cellulose paper for promoting copper-catalyzed [3+2]-cycloadditions of organic azides with alkynes and adsorbing residual copper species in solution was developed. The thiol-grafted cellulose

NOVEL CONDENSED PYRAZOLE DERIVATIVE AND MEDICAL USES THEREOF

PROBLEM TO BE SOLVED: To provide a preventive or therapeutic agent for mood disorder, anxiety disorder, schizophrenia, dementia, drug dependence or the like related to subtypes of metabolism type glutamate receptor (mGlu) 2 and 3. SOLUTION: There are prov

Tricolor emission of a fluorescent heteroditopic ligand over a concentration gradient of zinc(II) ions

The internal charge transfer (ICT) type fluoroionophore arylvinyl-bipy (bipy = 2,2′-bipyridyl) is covalently tethered to the spirolactam form of rhodamine to afford fluorescent heteroditopic ligand 4. Compound 4 can be excited in the visible region, the e

METABOTROPIC GLUTAMATE RECEPTOR MODULATORS

The invention relates to heterocyclic derivatives of formula (I) as well as their pharmaceutically acceptable salts. The invention further relates to a process for the preparation of such compounds. The compounds of the invention are mGluR5 modulators and are therefore useful for the control and prevention of acute and/or chronic neurological disorders wherein Y, W, R1, R2 and R3 are as defined in claim 1.

CHEMICAL COMPOUNDS

The present invention discloses pyrimidine derivatives, compositions and medicaments containing the same, as well as processes for the preparation and use of such compounds, compositions and medicaments. Such pyrimidine derivatives are useful in the treat

Molecular recognition of β-ribofuranosides by synthetic polypyridine-macrocyclic receptors

Artificial ribofuranoside receptors were designed and synthesized. The design of the polypyridine-macrocyclic receptors was based on the multipoint hydrogen bond complementarity between the receptors and methyl β-D-ribofuranoside. The binding affinity of the receptors for the ribofuranoside in CDCl3 was very high (up to K(a) = 5.2 x 103 M-1), so that even native ribose was extracted by them into such nonpolar solvents. Selective extraction of ribose by the receptors was observed: the extractabilities, or affinities to the receptors of various pentoses and hexoses decreased in the following order: ribose > deoxyribose ? lyxose ? xylose > fructose > arabinose > glucose ? mannose ? galactose. The selectivity is governed by the OH direction and the whole size of the sugars as well as their shapes. Furthermore, fluorescence emission of the receptors was largely enhanced in the presence of methyl β-D-ribofuranoside or ribose, and the degree for the fluorescence enhancement by the addition of various sugars was almost compatible with that of the extractabilities. The polypyridine-macrocycles represent rationally designed multifunctional artificial receptors for ribofuranosides.