17332-70-6 Usage
General Description
7-Methyl-DL-Tryptophan, also known as 1-Methyl-DL-Tryptophan or Indoximod, is a derivative of the essential amino acid tryptophan that is often used in studies related to immunology and cancer treatment. It is recognized as an immunomodulatory drug that has the potential to hinder specific enzymes, regulating the immune response against cancer cells. In numerous types of cancers, it has been shown to inhibit the indoleamine 2,3-dioxygenase (IDO) pathway, thereby suppressing tumor growth. It is frequently used in preclinical and clinical studies and is typically administered orally.
Check Digit Verification of cas no
The CAS Registry Mumber 17332-70-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,3 and 2 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17332-70:
(7*1)+(6*7)+(5*3)+(4*3)+(3*2)+(2*7)+(1*0)=96
96 % 10 = 6
So 17332-70-6 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O2/c1-7-3-2-4-9-8(6-14-11(7)9)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)/t10-/m0/s1
17332-70-6Relevant articles and documents
Synthesis method of 7-methyltryptophan
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, (2020/12/30)
The invention provides a synthesis method of 7-methyl tryptophan, which comprises the following steps: (1) reacting a compound a with a compound b to obtain a compound 1; (2) reacting the compound 1 with water to obtain a compound 2; (3) reacting the compound 2 with hydrogen to obtain a compound 3; and (4) carrying out hydrolysis reaction on the compound 3 to obtain the 7-methyl tryptophan. The method has the advantages of cheap and accessible raw materials, mild reaction conditions, simple equipment requirements and high safety index, and is suitable for large-scale commercial production. Thetotal yield of the 7-methyl tryptophan prepared by the method is as high as 52.6%, and the purity of the 7-methyl tryptophan is as high as 98%. The invention provides a new choice for the commercialproduction process of the 7-methyl tryptophan medicinal intermediate.
