173390-89-1Relevant academic research and scientific papers
A detailed investigation of the preparation of 2,7-diaminosuberic acid and 2,5-diaminoadipic acid derivatives using Kolbe electrolysis
Hiebl, Johann,Blanka, Michael,Guttman, Andras,Kollmann, Hermann,Leitner, Kornelia,Mayrhofer, Guenter,Rovenszky, Franz,Winkler, Karin
, p. 2059 - 2074 (2007/10/03)
The yield of protected 2,7-diaminosuberic acid (DAS) prepared by Kolbe reaction of N-protected α-glutamic acid esters is dependent on solvent, temperature, concentration of carboxylate onion, and protecting groups. The highest yield of protected L,L-2,7-diaminosuberic acid is obtained with Boc-Glu-OMe as starting material using MeOH/pyridine/NaOMe as electrolyte.
