173398-07-7

Upstream product

• 400782-36-7 t-butyl (+)-3-hydroxy-3-phenyl-2-<(R)-p-tolylsulfinyl>propionate 
• 400782-30-1 t-butyl (-)-3-hydroxy-3-phenyl-2-<(S)-p-tolylsulfinyl>propionate 
• 163460-81-9 tert-butyl (E)-[(S)-p-tolylsulfinyl]cinnamate 
• 163460-82-0 tert-butyl (E)-[(R)-p-tolylsulfinyl]cinnamate 
• 173313-22-9 (S)-(-)-4-phenyl-1,5-diazabicyclo<3.3.1>octan-2-one 
• 173313-23-0 (R)-(+)-4-phenyl-1,5-diazabicyclo<3.3.1>octan-2-one 

Downstream Products

• 173398-08-8 (R)-(-)-5-methyl-4-phenyl-1,5-diazacyclooctan-2-one 
• 20410-93-9 1,1'-(butane-1,4-diyl)bis[hexahydro-5-methyl-4-phenyl-1,5-diazocin-2(1H)-one] 

Relevant academic research and scientific papers

Asymmetric synthesis of 4-phenyl-1,5-diazacyclooctan-2-one using optically active vinyl sulfoxides

Both enantiomers of (S)- and (R)-4-phenyl-1,5-diazacyclooctan-2-ones (7) were synthesized stereoselectively with good optical purity by the asymmetric conjugate addition of pyrazolidine to optically active vinyl sulfoxides, t-butyl (E)-2-[(R)- and (S)-p-tolylsulfinyl]cinnamates, respectively. Starting from 7, a synthesis of optically active homaline was achieved.