17351-16-5

Basic information

• Product Name: trans-1,2-bis(hydroxydiphenylmethyl)cyclohexane
• CAS NO: 17351-16-5
• Molecular Weight: 448.605
• Mol File: 17351-16-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: trans-1,2-bis(hydroxydiphenylmethyl)cyclohexane(CAS DataBase Reference)
• NIST Chemistry Reference: trans-1,2-bis(hydroxydiphenylmethyl)cyclohexane(17351-16-5)
• EPA Substance Registry System: trans-1,2-bis(hydroxydiphenylmethyl)cyclohexane(17351-16-5)

Safety Data

• Hazardous Substances Data: 17351-16-5(Hazardous Substances Data)

Upstream product

• 96836-97-4 diethyl cyclohexane-trans-1,2-dicarboxylate 
• 591-51-5 phenyllithium 
• 2305-32-0 trans-1,2-cyclohexanedicarboxylic acid 
• 3205-35-4 trans dimethyl cyclohexane-1,2-dicarboxylate 
• 104722-26-1 trans-1,2-dibenzoylcyclohexane 
• 17351-07-4 diethyl cyclohexane-cis-1,2-dicarboxylate 

Downstream Products

• 17351-18-7 1,1,3,3-tetraphenyl-cis-octahydro-isobenzofuran 
• 880073-86-9 cis-1.2-bis-(α-methoxy-benzhydryl)-cyclohexane 
• 119-61-9 benzophenone 
• 91-01-0 1,1-Diphenylmethanol 
• 110-83-8 cyclohexene 
• 27621-80-3 1,2-Bis-diphenylmethylen-cyclohexan 
• 17351-18-7 (+/-)-1,1,3,3-tetraphenyl-trans-octahydro-isobenzofuran 
• 17351-18-7 (S)-1,1,3,3-tetraphenyl-trans-octahydro-isobenzofuran 

Relevant articles and documents

Synthesis of α,β-unsaturated dioxanes, dioxolanes and dioxepanes by trans-acetalisation of dimethylacetals with meso or C 2-symmetrical 1,2-, 1,3- and 1,4-diols

Several o-dibenzylic diols were prepared reacting organometallics with o-phthalaldehyde at room temperature in ether. The identity of the meso and C2-symmetrical (D,L) isomers as well as their ratio were determined by chiral gas chromatography. The meso and C2 (racemic) stereoisomeric diols were easily separated by flash chromatography on silica gel. A set of 18 α,β-unsaturated acetals were then prepared reacting those, as well as commercially available 1,2, 1,3 and 1,4 diols, with the corresponding methylacetals in acidic medium. A trans-acetalisation procedure adapted to the cases of fragile allylic alcohols or unfavorable 1,6 diols-derived dioxonanes based on a Dean-Stark trapping of methanol was also employed.