173532-06-4Relevant academic research and scientific papers
Ring expansion of cyclic β-amino alcohols induced by diethylaminosulfur trifluoride: Synthesis of cyclic amines with a tertiary fluorine at C3
Anxionnat, Bruno,Robert, Benoit,George, Pascal,Ricci, Gino,Perrin, Marc-Antoine,Gomez Pardo, Domingo,Cossy, Janine
, p. 6087 - 6099 (2012/09/11)
As the replacement of a hydrogen atom by a fluorine atom in a compound can have an important impact on its biological properties, the development of methods allowing the introduction of a fluorine atom is of great importance. The scope and limitations of
CH activation and CH2 double activation of indolines by radical translocation: Understanding the chemistry of the indolinyl radical
Harrowven, David C.,Stenning, Kerri J.,Whiting, Sally,Thompson, Toby,Walton, Robert
, p. 4882 - 4885 (2011/08/05)
CH activation and CH2 double activation of indolines at C2 may be achieved efficiently through radical translocation. The fate of the C2 indolinyl radical is dictated by the substitution at C3. Fragmentation, cyclisation and tandem cyclisation reactions leading to indole, azaheterocycle and azapropellane formation, respectively, are reported. The Royal Society of Chemistry 2011.
