173537-56-9Relevant academic research and scientific papers
Synthesis of Calixarenes Partially Functionalized at the Upper Rim
Casnati, Alessandro,Domiano, Laura,Pochini, Andrea,Ungaro, Rocco,Carramolino, Mar,et al.
, p. 12699 - 12720 (1995)
Several new examples of calixarenes selectively functionalized at the upper rim are reported.Starting from calixarenes 1,3,5-tri-, 1,2,4,5-tetra- and 1,2,3,4,5-pentaalkylated at the lower rim, it is possible to isolate macrocycles 2,4,6-tri-, 3,6-di- and 6-mono functionalized at the upper rim (18-94 percent yield) with nitro, formyl, bromo, chloromethyl and 2-propenyl groups.Modifications of these moieties allow the synthesis of macrocycles bearing amino, amido, hydroxymethyl, carboxy, cyano and chloromethyl functions which can be used for further transformation and preparation of new molecular receptors, based on calixarenes, which have different geometries.Examples of di- and triquinones on the hexameric macrocycle are also reported.
