17355-68-9

Basic information

• Product Name: 1-(4-chlorophenyl)-3,5-diphenyl-1H-1,2,4-triazole
• Synonyms: 1-(4-chlorophenyl)-3,5-diphenyl-1H-1,2,4-triazole
• CAS NO: 17355-68-9
• Molecular Weight: 331.804
• Mol File: 17355-68-9.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 1-(4-chlorophenyl)-3,5-diphenyl-1H-1,2,4-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-chlorophenyl)-3,5-diphenyl-1H-1,2,4-triazole(17355-68-9)
• EPA Substance Registry System: 1-(4-chlorophenyl)-3,5-diphenyl-1H-1,2,4-triazole(17355-68-9)

Safety Data

• Hazardous Substances Data: 17355-68-9(Hazardous Substances Data)

Upstream product

• 100-47-0 benzonitrile 
• 1073-69-4 N-4-chlorophenylhydrazine 
• 100-52-7 benzaldehyde 
• 2833-68-3 benzaldehyde-p-chlorophenylhydrazone 
• 100-46-9 benzylamine 
• 106-47-8 4-chloro-aniline 
• 7035-69-0 N-(4-chlorophenyl)benzamidine 

Relevant articles and documents

An Electrochemical Way to Generate Amphiphiles from Hydrazones for the Synthesis of 1,2,4-Triazole Scaffold Cyclic Compounds

An electro-oxidative cyclization pathway in which hydrazones are selected as starting materials to generate amphiphiles by reacting with benzylamines and benzamides was reported. This strategy successfully prepared a series of 1,2,4-triazoles in satisfact

A practical base mediated synthesis of 1,2,4-triazoles enabled by a deamination annulation strategy

A rapid and efficient base mediated synthesis of 1,3,5-trisubstituted 1,2,4-triazoles has been developed using the annulation of nitriles with hydrazines, which can be expanded to a wide range of triazoles in good to excellent yields. Ammonia gas is liberated during the reaction, and halo and hetero functional groups as well as free hydroxyl and amino groups are tolerated in this transformation. A variety of alkyl and aryl-substituted nitriles can be functionalized with aromatic and aliphatic hydrazines employing this procedure. This finding provides a practical and useful strategy for the synthesis of various 15N-labeled 1,2,4-triazole derivatives, and two types of mGlu5 receptor pharmaceuticals can be easily assembled in a one-pot manner. This journal is

Direct Access to 1,3,5-Trisubstituted 1 H -1,2,4-Triazoles from N -Phenylbenzamidines via Copper-Catalyzed Diamination of Aryl Nitriles

A copper-catalyzed formation of C-N/N-N bonds using N-phenylbenzamidines with aryl nitriles has been developed and affords a route to 1,3,5-trisubstituted 1H-1,2,4-triazoles in moderate to excellent yields. The method is operationally simple and environme