173554-21-7Relevant academic research and scientific papers
MTORC MODULATORS AND USES THEREOF
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, (2020/08/13)
Novel rapamycin analogs and uses thereof are disclosed herein. The rapamycin analogs of the present disclosure show increased mTORC1 specificity and lowered mTORC2 specificity relative to rapamycin.
RAPAMYCIN ANALOGS AS ANTI-CANCER AGENTS
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Page/Page column 46, (2009/12/05)
Analogs and derivatives of rapamycin are provided, wherein the analogs and derivatives can bind to FK-506 binding protein (FKBP), or inhibit the mTOR function of an FKBP, or both. The analogs and derivatives are rapamycin include the rapamycin skeleton su
