1736-85-2

Usage

Uses

Used in Pharmaceutical Industry:
2-Fluoro-1,3-diMethyl-5-nitrobenzene is used as a key intermediate in the synthesis of (benzoylaminophenoxy)phenol derivatives, which are known as androgen receptor antagonists. These antagonists play a crucial role in the development of medications targeting hormonal imbalances and conditions related to androgen receptors, such as prostate cancer and other androgen-dependent disorders.

InChI:InChI=1S/C8H8FNO2/c1-5-3-7(10(11)12)4-6(2)8(5)9/h3-4H,1-2H3

Upstream product

• 443-88-9 2-fluoro-m-xylene 
• 156740-78-2 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate 
• 2423-71-4 2,6-dimethyl-4-nitro phenol 

Downstream Products

• 1840-27-3 4-fluoro-3,5-dimethyl-benzenamine 
• 361435-65-6 5-(2,6-dimethyl-4-nitrophenoxy)-3-isopropyl-1H-indole 
• 404919-08-0 5-(2,6-dimethyl-4-nitrophenoxy)-3-pentyl-1H-indazole 
• 482308-12-3 4-(4-amino-2,6-dimethylphenyl)-3-morpholinone 
• 1093183-62-0 3-bromo-1-(2,6-dimethyl-4-nitrophenyl)pyridin-2(1H)-one 
• 1093655-74-3 1-(2,6-dimethyl-4-nitrophenyl)-3-methoxy-pyridin-2(1H)-one 
• 1393125-32-0 3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)benzenamine 
• 1393122-96-7 (+/-)-3-(4-(1-(3,5-dimethyl-4-(4-(trifluoromethyl)-1H-pyrazol-1-yl)phenylamino)butyl)benzamido)propanoic acid 

Relevant academic research and scientific papers

New 4,4'-Bis(9-carbazolyl)-biphenyl derivatives with locked carbazole-biphenyl junctions: High-triplet state energy materials

We synthesized a series of 4,4'-bis(9-carbazolyl)-biphenyl (CBP) derivatives, using methyl groups as spatially demanding groups, locking the angle between the carbazole subunit and the biphenyl backbone as potential matrix material for blue organic light-

No-carrier-added [18F]fluoroarenes from the radiofluorination of diaryl sulfoxides

No-carrier-added [18F]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [18F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[18F]fluoroarenes in high RCYs. This process broadens the scope for preparing novel 18F-labeling synthons and PET radiotracers.