156740-78-2

Basic information

• Product Name: 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate
• Synonyms: 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate
• CAS NO: 156740-78-2
• Molecular Weight: 299.227
• Mol File: 156740-78-2.mol

Chemical Properties

• CAS DataBase Reference: 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate(156740-78-2)
• EPA Substance Registry System: 2,6-dimethyl-4-nitrophenyl trifluoromethanesulphonate(156740-78-2)

Safety Data

• Hazardous Substances Data: 156740-78-2(Hazardous Substances Data)

Upstream product

• 37595-74-7 N,N-phenylbistrifluoromethane-sulfonimide 
• 2423-71-4 2,6-dimethyl-4-nitro phenol 
• 358-23-6 trifluoromethylsulfonic anhydride 
• 1025373-45-8 trifluoromethanesulfonic acid anhydride 

Downstream Products

• 53906-84-6 2-bromo-1,3-dimethyl-5-nitrobenzene 
• 38560-96-2 2-chloro-1,3-dimethyl-5-nitro-benzene 
• 1393125-92-2 3,5-dimethyl-4-(4-(trifluoromethyl)-1H-imidazol-1-yl)phenol 
• 1393125-91-1 1-(2,6-dimethyl-4-nitrophenyl)-4-(trifluoromethyl)-1H-imidazole 
• 1425187-94-5 2,6-dimethyl-4-nitrophenyl(phenyl)sulfoxide 
• 1425187-95-6 2,6-dimethyl-4-nitrophenyl(4'-nitrophenyl)sulfoxide 
• 114660-00-3 2,6-dimethyl-4-nitrophenyl (phenyl) sulfide 
• 1425187-97-8 2,6-dimethyl-4-nitrophenyl (4'-nitrophenyl) sulfide 
• 1736-85-2 2-fluoro-1,3-dimethyl-5-nitrobenzene 
• 1425188-03-9 C₈H₈⁽¹⁸⁾FNO₂ 

Relevant articles and documents

New 4,4'-Bis(9-carbazolyl)-biphenyl derivatives with locked carbazole-biphenyl junctions: High-triplet state energy materials

We synthesized a series of 4,4'-bis(9-carbazolyl)-biphenyl (CBP) derivatives, using methyl groups as spatially demanding groups, locking the angle between the carbazole subunit and the biphenyl backbone as potential matrix material for blue organic light-

No-carrier-added [18F]fluoroarenes from the radiofluorination of diaryl sulfoxides

No-carrier-added [18F]fluoroarenes were synthesized through the radiofluorination of diaryl sulfoxides with [18F]fluoride ion. Diaryl sulfoxides bearing a para electron-withdrawing substituent readily gave the corresponding 4-[18F]fluoroarenes in high RCYs. This process broadens the scope for preparing novel 18F-labeling synthons and PET radiotracers.

GLUCAGON RECEPTOR MODULATORS

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.

Glucagon Receptor Modulators

The present invention provides a compound of Formula (I) or a pharmaceutically acceptable salt thereof wherein R1, R2, R3, A1, A2, A3, A4, L, B1, B2, B3 and B4 are as defined herein. The compounds of Formula I have been found to act as glucagon antagonists or inverse agonists. Consequently, the compounds of Formula I and the pharmaceutical compositions thereof are useful for the treatment of diseases, disorders, or conditions mediated by glucagon.

Therapeutic modulation of PPARgamma activity

Modulators of PPARγ activity are used in methods of treating and/or preventing conditions such as osteoporosis, Alzheimer's disease, psoriasis and acne, and cancer.

3-(4-BENZYLOXYPHENYL)PROPANOIC ACID DERIVATIVES

The present invention provides a novel compound represented by the formula (I) wherein each symbol is as defined in the specification, a salt thereof and a prodrug thereof having a superior GPR40 receptor function modulating action, which can be used as an insulin secretagogue, an agent for the prophylaxis or treatment of diabetes and the like. They unexpectedly show superior GPR40 receptor agonist activity, and also show superior properties as a pharmaceutical product, such as stability and the like. Thus, they can be safe and useful pharmaceutical agents for the prophylaxis or treatment of GPR40 receptor related diseases in mammals.

Diphenylmethane derivatives

The invention relates to novel diphenylmethane derivatives, processes for their preparation and their use in medicaments, in particular for the indications of arteriosclerosis and hypercholesterolaemia.

A soluble polymer-supported triflating reagent: a high-throughput synthetic approach to aryl and enol triflates.

[reaction: see text] The high-yielding synthesis and application of the first example of a polymer-supported reagent for the preparation of trifluoromethanesulfonates (triflates) is described. This new reagent efficiently triflates aryl alcohols and lithi

RETROVIRAL PROTEASE INHIBITING COMPOUNDS

A compound of the formula: STR1 is disclosed as a retroviral protease inhibitor compound. Also disclosed are methods and compositions for inhibiting an HIV infection.

Heteroacetic acid derivatives

Disclosed are compounds of formula STR1 wherein R is hydroxy, esterified hydroxy or etherified hydroxy; R1 is halogen, trifluoromethyl or lower alkyl; R2 is halogen, trifluoromethyl or lower alkyl; R3 is halogen, trifluoromethyl, lower alkyl, aryl, aryl-lower alkyl, cycloalkyl or cycloalkyl-lower alkyl; or R3 is the radical STR2 wherein R8 is hydrogen, lower alkyl, aryl, cycloalkyl, aryl-lower alkyl or cycloalkyl-lower alkyl; R9 is hydroxy or acyloxy; R10 represents hydrogen or lower alkyl; or R9 and R10 together represent oxo; R4 is hydrogen, halogen, trifluoromethyl or lower alkyl; X is --NR7, S or O; W is O or S; R5 represents hydrogen, lower alkyl or aryl-lower alkyl;and R6 represents hydrogen; or R5 and R6 together represent oxo provided that X represents --NR7; R7 represents hydrogen or lower alkyl; Z represents carboxyl, carboxyl derivatized as a pharmaceutically acceptable ester or as a pharmaceutically acceptable amide; and pharmaceutically acceptable salts thereof; which are useful as hypocholesteremic agents.