173690-53-4 Usage
Description
FMOC-(4-aminophenyl)acetic acid is a chemical compound that features a fluorenylmethyloxycarbonyl (FMOC) group attached to a 4-aminophenylacetic acid molecule. FMOC-(4-AMINOPHENYL)ACETIC ACID is recognized for its utility in the protection of amines during peptide synthesis, with the FMOC group being easily removable under mild conditions. The 4-aminophenylacetic acid component also functions as a versatile building block for the creation of a range of organic molecules and pharmaceuticals, highlighting the compound's multifaceted role in organic chemistry and pharmaceutical development.
Uses
Used in Peptide Synthesis:
FMOC-(4-aminophenyl)acetic acid is used as a protecting group for amines in peptide synthesis. Its application is crucial for preventing unwanted side reactions during the synthesis process, ensuring the correct formation of peptide bonds and facilitating the production of the desired peptide sequence.
Used in Organic Chemistry:
In the realm of organic chemistry, FMOC-(4-aminophenyl)acetic acid serves as a valuable intermediate. Its 4-aminophenylacetic acid component is a key building block for synthesizing a variety of organic molecules, contributing to the development of new compounds with potential applications in various fields.
Used in Pharmaceutical Compounds Synthesis:
FMOC-(4-AMINOPHENYL)ACETIC ACID is also utilized in the synthesis of pharmaceutical compounds, where its structural elements can be incorporated into drug molecules to enhance their therapeutic properties or improve their pharmacokinetic profiles.
Used in Research and Development:
FMOC-(4-aminophenyl)acetic acid is employed in research and development settings to explore new methods of peptide synthesis and to study the properties of the FMOC protecting group and its impact on the synthesis process.
Check Digit Verification of cas no
The CAS Registry Mumber 173690-53-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,3,6,9 and 0 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 173690-53:
(8*1)+(7*7)+(6*3)+(5*6)+(4*9)+(3*0)+(2*5)+(1*3)=154
154 % 10 = 4
So 173690-53-4 is a valid CAS Registry Number.
173690-53-4Relevant articles and documents
Solid-phase synthesis of disubstituted guanidines
Kearney, Patrick C.,Fernandez, Monica,Flygare, John A.
, p. 2663 - 2666 (1998)
A method for the solid-phase synthesis of disubstituted guanidines is reported. In this procedure, polymer-bound aryl or alkyl amines are converted to methyl isothioureas in three steps and treated with primary and secondary amines to form the disubstitut
Virtues of Volatility: A Facile Transesterification Approach to Boronic Acids
Hinkes, Stefan P.A.,Klein, Christian D.P.
supporting information, p. 3048 - 3052 (2019/05/10)
Boronic acids are an increasingly important compound class for many applications, including C-C bond formation reactions, medicinal chemistry, and diagnostics. The deprotection of boronic ester intermediates is frequently a problematic and inefficient step in boronic acid syntheses. We describe an approach that highly facilitates this transformation by leveraging the volatility of methylboronic acid and its diol esters. The method is performed under mild conditions, provides high yields, and eliminates cumbersome and problematic purification steps.
Preparation of 16β-estradiol derivative libraries as bisubstrate inhibitors of 17β-hydroxysteroid dehydrogenase type 1 using the multidetachable sulfamate linker
Berube, Marie,Delagoutte, Florian,Poirier, Donald
experimental part, p. 1590 - 1631 (2010/05/17)
Combinatorial chemistry is a powerful tool used to rapidly generate a large number of potentially biologically active compounds. In our goal to develop bisubstrate inhibitors of 17β-hydroxysteroid dehydrogenase type 1 (17β-HSD1) that interact with both th
