17374-09-3 Usage
Structure
Thiazole derivative with a sulfur atom, a mercapto group, and two phenyl groups attached to the thiazole ring
Usage
Building block in the synthesis of pharmaceuticals, agrochemicals, and materials; reagent in organic synthesis; intermediate in the production of dyes and pigments
Potential applications
Medicinal chemistry and materials science research.
Check Digit Verification of cas no
The CAS Registry Mumber 17374-09-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,7 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 17374-09:
(7*1)+(6*7)+(5*3)+(4*7)+(3*4)+(2*0)+(1*9)=113
113 % 10 = 3
So 17374-09-3 is a valid CAS Registry Number.
17374-09-3Relevant articles and documents
Azole derivatives as histamine H3 receptor antagonists, Part 2: C-C and C-S coupled heterocycles
Walter,Isensee,Kottke,Ligneau,Camelin,Schwartz,Stark
scheme or table, p. 5883 - 5886 (2010/11/18)
With a small series of compounds we demonstrated the variability in the core region of the human histamine H3 receptor (hH3R) antagonist structural blueprint by introducing polar azole groups (oxazole, oxadiazole, thiazole and triazole). Additional variations achieved by coupling different residues to the heterocyclic core structure led to further optimisation of in vitro receptor binding of the novel azole derivatives.
