173780-27-3

Upstream product

• 29582-31-8 (E)-4-(4-ethoxyphenyl)-4-oxobut-2-enoic acid 
• 173780-26-2 β-(4-Ethoxybenzoyl)-α-(1,3-diphenyl-5(4H)-oxo-pyrazolin-4-yl)propionic acid 

Downstream Products

• 173780-31-9 3-Chloro-4,5-dihydro-6-(4-ethoxyphenyl)-4-(5-chloro-1,3-diphenyl-pyrazolin-4-yl)pyridazine 
• 173780-34-2 4,5-Dihydro-3-hydrazino-6-(4-ethoxyphenyl)-4-(1,3-diphenyl-5-hydrazinopyrazolin-4-yl)pyridazine 

Relevant academic research and scientific papers

Synthesis and Biological Activity of some new Pyridazine Derivatives

Condensation of β-aroyl-α- propionic acid with hydrazine hydrate affords 4,5-dihydro-3(2H)-pyridazinone (2).Reaction of 2 with POCl3 and P2S5 gives a dichloro derivative (7) and a dithione (4).The behavior of the dichloro and dithione derivatives toward various reagents was studied.The in vitro antibacterial screening reveals moderate activities against certain bacteria. - Keywords: Pyridazinone; Pyridazinethione; Chlorpyridiazine