173780-34-2Relevant academic research and scientific papers
Synthesis and Biological Activity of some new Pyridazine Derivatives
AbdEl-Ghani, E.,Assy, M. G.,Moustafa, H. Y.
, p. 1265 - 1270 (2007/10/03)
Condensation of β-aroyl-α- propionic acid with hydrazine hydrate affords 4,5-dihydro-3(2H)-pyridazinone (2).Reaction of 2 with POCl3 and P2S5 gives a dichloro derivative (7) and a dithione (4).The behavior of the dichloro and dithione derivatives toward various reagents was studied.The in vitro antibacterial screening reveals moderate activities against certain bacteria. - Keywords: Pyridazinone; Pyridazinethione; Chlorpyridiazine
