17379-38-3 Usage
General Description
3-(trimethylsilyl)pyridine-4-carbonitrile is a chemical compound with the molecular formula C9H11NSi. It is a derivative of pyridine and has a trimethylsilyl group attached to the fourth carbon atom, as well as a cyano group attached to the nitrogen atom. 3-(TRIMETHYLSILYL)PYRIDINE-4-CARBONITRILE is commonly used as a reagent in organic synthesis, particularly in the form of the trimethylsilyl group, which can serve as a protecting group for reactive functional groups, such as hydroxyl or amino groups, during chemical reactions. It also has the potential to be used in the pharmaceutical industry for the synthesis of biologically active molecules. Additionally, 3-(trimethylsilyl)pyridine-4-carbonitrile has been studied for its potential use in the field of materials science for the construction of functional organic materials.
Check Digit Verification of cas no
The CAS Registry Mumber 17379-38-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,7 and 9 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17379-38:
(7*1)+(6*7)+(5*3)+(4*7)+(3*9)+(2*3)+(1*8)=133
133 % 10 = 3
So 17379-38-3 is a valid CAS Registry Number.
InChI:InChI=1/C9H12N2Si/c1-12(2,3)9-7-11-5-4-8(9)6-10/h4-5,7H,1-3H3
17379-38-3Relevant articles and documents
Transition-Metal-Free Cross-Coupling of Aryl and N-Heteroaryl Cyanides with Benzylic Zinc Reagents
Quinio, Pauline,Roman, Daniela Sustac,León, Thierry,William, Sharankini,Karaghiosoff, Konstantin,Knochel, Paul
supporting information, p. 4396 - 4399 (2015/09/15)
Functionalized 4-benzylated pyridines can be efficiently prepared by a transition-metal-free cross-coupling between various benzylic zinc chlorides and substituted 4-cyanopyridines in THF/DMPU under microwave irradiation (40 °C, 0.5-1.5 h). Selective benzylations on polycyano-aromatics have also been achieved under these mild conditions. We also report a novel oxidative nucleophilic substitution of a hydrogen on 1,3-dicyanobenzene using benzylic zinc reagents.
