17380-31-3

Basic information

• Product Name: 3-Benzyl-1H-indole-5-carbonitrile
• Synonyms: 3-Benzyl-1H-indole-5-carbonitrile
• CAS NO: 17380-31-3
• Molecular Formula: C₁₆H₁₂N₂
• Molecular Weight: 232.27988
• Mol File: 17380-31-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 452.9°Cat760mmHg
• Flash Point: 145.4°C
• Appearance: /
• Density: 1.22g/cm³
• Vapor Pressure: 2.15E-08mmHg at 25°C
• Refractive Index: 1.684
• CAS DataBase Reference: 3-Benzyl-1H-indole-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Benzyl-1H-indole-5-carbonitrile(17380-31-3)
• EPA Substance Registry System: 3-Benzyl-1H-indole-5-carbonitrile(17380-31-3)

Safety Data

• Hazardous Substances Data: 17380-31-3(Hazardous Substances Data)

Usage

InChI:InChI=1/C16H12N2/c17-10-13-6-7-16-15(9-13)14(11-18-16)8-12-4-2-1-3-5-12/h1-7,9,11,18H,8H2

Upstream product

• 15861-24-2 1H-indole-5-carbonitrile 
• 100-39-0 benzyl bromide 
• 787631-74-7 3-(hydroxyphenylmethyl)indole-5-carbonitrile 
• 100-51-6 benzyl alcohol 

Downstream Products

• 787631-89-4 C₂₈H₂₅BrN₂O₂ 

Relevant articles and documents

Rapid and general protocol towards catalyst-free friedel-crafts C-alkylation of indoles in water assisted by microwave irradiation

An efficient and simplified protocol for uncatalyzed FriedelCrafts alkylation of indoles using microwave irradiation in water is described. A series of functionalized indole derivatives has been synthesized in very short times with moderate to good yields. The combination of microwave irradiation and superheated water offers significant advantages over conventional methods, such as higher selectivities, simplicity, shorter reaction times, and no need for a catalyst.

Biarylmethyl indolines, indoles and tetrahydroquinolines, useful as serine protease inhibitors

The present invention provides compounds of Formula (I): or a stereoisomer or pharmaceutically acceptable salt or hydrate form thereof, wherein the variables A, B, L1, L2, X1, X2, X3, X4 an