17380-80-2

Basic information

• Product Name: Cyclohexanamine, 1-(4-fluorophenyl)-
• CAS NO: 17380-80-2
• Molecular Formula: C12H16FN
• Molecular Weight: 193.264
• Mol File: 17380-80-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Cyclohexanamine, 1-(4-fluorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanamine, 1-(4-fluorophenyl)-(17380-80-2)
• EPA Substance Registry System: Cyclohexanamine, 1-(4-fluorophenyl)-(17380-80-2)

Safety Data

• Hazardous Substances Data: 17380-80-2(Hazardous Substances Data)

Upstream product

• 460-00-4 1-Bromo-4-fluorobenzene 
• 108-94-1 cyclohexanone 
• 352-13-6 4-flourophenylmagnesium bromide 
• 1496-36-2 1-(4-fluorophenyl)cyclohexan-1-ol 
• 17380-57-3 N-[1-(4-fluoro-phenyl)-cyclohexyl]-formamide 
• 111-24-0 1,5-dibromo-pentane 
• 71486-43-6 1-(4-fluorophenyl)cyclohexanecarbonitrile 
• 459-22-3 4-fluorophenylacetonitrile 

Downstream Products

• 33082-88-1 N-<2-Chlor-aethyl>-N'-<1-(4-fluor-phenyl)-cyclohexyl>-harnstoff 

Relevant articles and documents

Synthesis method of six-membered ring benzylamine compound

The invention relates to the field of synthesis of organic matters, and particularly discloses a synthesis method of a six-membered ring benzylamine compound, which comprises the following steps: taking a compound D, a compound E and potassium tert-butoxide as raw materials, taking dimethyl sulfoxide as a solvent, reacting at 5-10 DEG C for 1-2 hours, heating to 20 DEG C, reacting, and purifying and separating after the reaction is finished to obtain a compound A; the method comprises the following steps: by taking a compound A, potassium carbonate and hydrogen peroxide as raw materials and dimethyl sulfoxide as a solvent, reacting at 50-65 DEG C, adding ice water to separate out a product after the reaction is finished, filtering and washing to obtain a compound B; dissolving the compound B in acetonitrile, adjusting the pH value to 13-14, adding a saturated sodium hypochlorite solution for reaction, and purifying and washing after the reaction is finished to obtain a compound C; the method has the effect of improving the defect that the synthesis process of the six-membered ring benzylamine compound is not suitable for industrial production.