173844-27-4Relevant academic research and scientific papers
Structure-activity relationships study of two series of leukotriene B4 antagonists: Novel indolyl and naphthyl compounds substituted with a 2- [methyl(2-phenethyl)amino]-2-oxoethyl side chain
Chan, Wan K.,Huang, Fu-Chih,Morrissette, Matthew M.,Warus, James D.,Moriarty, Kevin J.,Galemmo, Robert A.,Dankulich, William D.,Poli, Gregory,Sutherland, Charles A.
, p. 3756 - 3768 (2007/10/03)
N-Methyl-N-phenethylphenylacetamide has been reported to be a key binding domain to LTB4 receptors. Here we describe the synthesis and structure-activity relationship (SAR) studies of two new series of LTB4 receptor antagonists in wh
SUBSTITUTED NAPHTHYLENE COMPOUNDS EXHIBITING SELECTIVE LEUKOTRIENE B4 ANTAGONIST ACTIVITY
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, (2008/06/13)
This invention relates to bicyclic aryl compounds having selective LTB. sub.4 antagonist properties and comprising an amido substituent, a substituent group having a terminal carboxylic acid or derivative thereof and a lipophilic substituent, and to metho
