173901-10-5Relevant academic research and scientific papers
Human beta3 adrenergic receptor agonists containing cyclic ureidobenzenesulfonamides.
Parmee,Naylor,Perkins,Colandrea,Ok,Candelore,Cascieri,Deng,Feeney,Forrest,Hom,MacIntyre,Miller,Stearns,Strader,Tota,Wyvratt,Fisher,Weber
, p. 749 - 754 (2007/10/03)
Human beta3 adrenergic receptor agonists containing 5-membered ring ureas were shown to be potent partial agonists with excellent selectivity over beta1 and beta2 binding. L-760,087 (4a) and L-764,646 (5a) (beta3 EC50 = 18 and 14 nM, respectively) stimula
SUBSTITUTED SULFONAMIDES AS SELECTIVE BETA-3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
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, (2008/06/13)
Substituted sulfonamides are selective β 3 adrenergic receptor agonists with very little β 1 and β 2 adrenergic receptor activity and as such the compounds are capable of increasing lipolysis and energy expenditure in cells. The compounds thus have potent
SUBSTITUTED SULFONAMIDES AS SELECTIVE BETA3 AGONISTS FOR THE TREATMENT OF DIABETES AND OBESITY
-
, (2008/06/13)
Substituted sulfonamides are selective β 3 adrenergic receptor agonists with very little β 1 and β 2 adrenergic receptor activity and as such the compounds are capable of increasing lipolysis and energy expenditure in cells. The compounds thus have potent
