6752-38-1 Usage
Uses
Used in Organic Synthesis:
4-(Chlorosulfonyl) phenyl isocyanate is used as a key reactant in the synthesis of complex organic compounds, contributing to the development of various chemical products.
Used in Pigment Production:
4-(CHLOROSULFONYL)PHENYL ISOCYANATE is employed as a precursor in the production of pigments, which are essential for coloring various materials and products.
Used in Pharmaceutical Industry:
4-(Chlorosulfonyl) phenyl isocyanate is used as a pharmaceutical intermediate, playing a crucial role in the synthesis of various drugs and medicinal compounds.
Used in Biologically Active Compounds:
It is utilized in the creation of biologically active compounds, which have potential applications in research, medicine, and other fields.
Check Digit Verification of cas no
The CAS Registry Mumber 6752-38-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,7,5 and 2 respectively; the second part has 2 digits, 3 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 6752-38:
(6*6)+(5*7)+(4*5)+(3*2)+(2*3)+(1*8)=111
111 % 10 = 1
So 6752-38-1 is a valid CAS Registry Number.
InChI:InChI=1/C7H4ClNO3S/c8-13(11,12)7-3-1-6(2-4-7)9-5-10/h1-4H
6752-38-1Relevant articles and documents
Practical chemoenzymatic synthesis of a 3-pyridylethanolamino β3 adrenergic receptor agonist
Chung, John Y. L.,Ho, Guo-Jie,Chartrain, Michel,Roberge, Chris,Zhao, Dalian,Leazer, John,Farr, Roger,Robbins, Micheal,Emerson, Kateeta,Mathre, David J.,McNamara, James M.,Hughes, David L.,Grabowski, Edward J. J.,Reider, Paul J.
, p. 6739 - 6743 (2007/10/03)
A chemoenzymatic synthesis of β3 agonist 1 suitable for large scale preparation is described. The key chiral 3-pyridylethanolamine intermediate (R)-7 was prepared via an improved Neber rearrangement and a yeast-mediated asymmetric reduction. The tetrazolone fragment of the molecule was constructed via a dipolar cycloaddition between 1-(cyclopentyl)-3-propylazide and p-chlorosulfonyl phenylisocyanate. Sulfonamide coupling of these two intermediates under Shotten-Baumann conditions, followed by a borane reduction of the amide afforded 1 in 20-32% overall yield from 3-acetylpyridine.
