17392-68-6 Usage
Description
1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE, a pyrrole-2,5-dione derivative with the molecular formula C11H9NO3, is a chemical compound that features a methoxyphenyl group. It is widely recognized in the field of organic chemistry for its role as a building block in the synthesis of pharmaceuticals and agrochemicals. 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE's potential biological activities, including anticancer and anti-inflammatory properties, have been the subject of research, highlighting its significance in medicinal and synthetic chemistry due to its structural and reactive characteristics.
Uses
Used in Pharmaceutical Industry:
1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is used as a key intermediate for the synthesis of various pharmaceuticals, leveraging its reactivity and structural features to contribute to the development of new drugs.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE serves as a building block for the creation of agrochemicals, potentially enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is utilized as a subject of study in medicinal chemistry for its potential biological activities, particularly in exploring its anticancer and anti-inflammatory properties, which could lead to advancements in treatment options.
Used in Synthetic Chemistry:
As a valuable intermediate, 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is instrumental in the preparation of diverse heterocyclic compounds, expanding the scope of synthetic chemistry and contributing to the discovery of novel chemical entities.
Check Digit Verification of cas no
The CAS Registry Mumber 17392-68-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,9 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17392-68:
(7*1)+(6*7)+(5*3)+(4*9)+(3*2)+(2*6)+(1*8)=126
126 % 10 = 6
So 17392-68-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO3/c1-15-9-5-3-2-4-8(9)12-10(13)6-7-11(12)14/h2-7H,1H3
17392-68-6Relevant articles and documents
The CH-π interactions of methyl ethers as a model for carbohydrate-N-heteroarene interactions
Li, Ping,Parker, Trent M.,Hwang, Jungwun,Deng, Fengyuan,Smith, Mark D.,Pellechia, Perry J.,Sherrill, C. David,Shimizu, Ken D.
, p. 5064 - 5067 (2014)
CH-π interactions have been cited as an important contributor to carbohydrate recognition. To determine whether N-heterocycles form stronger CH-π interactions, the interactions of methyl ether groups with heterocyclic and nonheterocyclic aromatic surfaces
Graphene Oxide as a Carbocatalyst for a Diels–Alder Reaction in an Aqueous Medium
Girish, Yarabhally R.,Pandit, Subrata,Pandit, Subhendu,De, Mrinmoy
supporting information, p. 2393 - 2398 (2017/09/11)
The Diels–Alder (DA) reaction, a [4+2] cycloaddition reaction, is highly important in synthetic organic chemistry and is frequently used in the synthesis of natural products containing six-membered rings. Herein, we report an efficient protocol for the DA reaction between 9-hydroxymethylanthracene and N-substituted maleimides using two-dimensional graphene oxide (GO) as a heterogeneous carbocatalyst in an aqueous medium at room temperature. High yields, a wide substrate scope, low temperature, excellent functional group tolerance, atom economy, and water as a green solvent are noteworthy features of this protocol. The heterogeneous GO catalyst can be easily recovered and used multiple times without any significant loss in catalytic activity.
Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B
Chen, Hai-Jun,Liu, Yong,Wang, Li-Na,Shen, Qiang,Li, Jia,Nan, Fa-Jun
scheme or table, p. 2876 - 2879 (2010/07/04)
Structural optimization and preliminary structure-activity relationship studies of a series of N-substituted maleimide fused-pyrazole analogues with Cdc25B inhibitory activity, starting from a high-throughput screening hit, are illustrated. A simplified 3,5-diacyl pyrazole analogue was obtained as the most potent compound (118, IC50 = 0.12 μM) with a 270-fold increase in potency.
