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17392-68-6

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17392-68-6 Usage

Description

1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE, a pyrrole-2,5-dione derivative with the molecular formula C11H9NO3, is a chemical compound that features a methoxyphenyl group. It is widely recognized in the field of organic chemistry for its role as a building block in the synthesis of pharmaceuticals and agrochemicals. 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE's potential biological activities, including anticancer and anti-inflammatory properties, have been the subject of research, highlighting its significance in medicinal and synthetic chemistry due to its structural and reactive characteristics.

Uses

Used in Pharmaceutical Industry:
1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is used as a key intermediate for the synthesis of various pharmaceuticals, leveraging its reactivity and structural features to contribute to the development of new drugs.
Used in Agrochemical Industry:
Similarly, in the agrochemical sector, 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE serves as a building block for the creation of agrochemicals, potentially enhancing crop protection and yield.
Used in Medicinal Chemistry Research:
1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is utilized as a subject of study in medicinal chemistry for its potential biological activities, particularly in exploring its anticancer and anti-inflammatory properties, which could lead to advancements in treatment options.
Used in Synthetic Chemistry:
As a valuable intermediate, 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE is instrumental in the preparation of diverse heterocyclic compounds, expanding the scope of synthetic chemistry and contributing to the discovery of novel chemical entities.

Check Digit Verification of cas no

The CAS Registry Mumber 17392-68-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,9 and 2 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 17392-68:
(7*1)+(6*7)+(5*3)+(4*9)+(3*2)+(2*6)+(1*8)=126
126 % 10 = 6
So 17392-68-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H9NO3/c1-15-9-5-3-2-4-8(9)12-10(13)6-7-11(12)14/h2-7H,1H3

17392-68-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 1-(2-METHOXY-PHENYL)-PYRROLE-2,5-DIONE

1.2 Other means of identification

Product number -
Other names 2-METHOXYPHENYLMALEIMIDE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17392-68-6 SDS

17392-68-6Relevant articles and documents

The CH-π interactions of methyl ethers as a model for carbohydrate-N-heteroarene interactions

Li, Ping,Parker, Trent M.,Hwang, Jungwun,Deng, Fengyuan,Smith, Mark D.,Pellechia, Perry J.,Sherrill, C. David,Shimizu, Ken D.

, p. 5064 - 5067 (2014)

CH-π interactions have been cited as an important contributor to carbohydrate recognition. To determine whether N-heterocycles form stronger CH-π interactions, the interactions of methyl ether groups with heterocyclic and nonheterocyclic aromatic surfaces

Graphene Oxide as a Carbocatalyst for a Diels–Alder Reaction in an Aqueous Medium

Girish, Yarabhally R.,Pandit, Subrata,Pandit, Subhendu,De, Mrinmoy

supporting information, p. 2393 - 2398 (2017/09/11)

The Diels–Alder (DA) reaction, a [4+2] cycloaddition reaction, is highly important in synthetic organic chemistry and is frequently used in the synthesis of natural products containing six-membered rings. Herein, we report an efficient protocol for the DA reaction between 9-hydroxymethylanthracene and N-substituted maleimides using two-dimensional graphene oxide (GO) as a heterogeneous carbocatalyst in an aqueous medium at room temperature. High yields, a wide substrate scope, low temperature, excellent functional group tolerance, atom economy, and water as a green solvent are noteworthy features of this protocol. The heterogeneous GO catalyst can be easily recovered and used multiple times without any significant loss in catalytic activity.

Discovery and structural optimization of pyrazole derivatives as novel inhibitors of Cdc25B

Chen, Hai-Jun,Liu, Yong,Wang, Li-Na,Shen, Qiang,Li, Jia,Nan, Fa-Jun

scheme or table, p. 2876 - 2879 (2010/07/04)

Structural optimization and preliminary structure-activity relationship studies of a series of N-substituted maleimide fused-pyrazole analogues with Cdc25B inhibitory activity, starting from a high-throughput screening hit, are illustrated. A simplified 3,5-diacyl pyrazole analogue was obtained as the most potent compound (118, IC50 = 0.12 μM) with a 270-fold increase in potency.

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