173960-47-9Relevant academic research and scientific papers
Synthesis of substituted 2,2′-bipyridines from 2-bromo- or 2-chloropyridines using tetrakis(triphenylphosphine)palladium(0) as a catalyst in a modified Negishi cross-coupling reaction
Kiehne,Bunzen,Staats,Luetzen
, p. 1061 - 1069 (2007)
A protocol for an efficient, modified Negishi cross-coupling strategy for substituted 2,2′-bipyridines employing tetrakis(triphenylphosphine) palladium(0) as a simple, commercially available, and relatively inexpensive catalyst for both 2-bromo- and 2-chl
Iridium/Bipyridine-Catalyzed ortho-Selective C-H Borylation of Phenol and Aniline Derivatives
Li, Hong-Liang,Kanai, Motomu,Kuninobu, Yoichiro
supporting information, p. 5944 - 5947 (2017/11/10)
An iridium-catalyzed ortho-selective C-H borylation of phenol and aniline derivatives has been successfully developed. Iridium/bipyridine-catalyzed C-H borylation generally occurred at the meta- and para-positions of aromatic substrates. Introduction of an electron-withdrawing substituent on the bipyridine-type ligand and a methylthiomethyl group on the hydroxy and amino groups of the phenol and aniline substrates, however, dramatically altered the regioselectivity, affording exclusively ortho-borylated products. The reaction proceeded in good to excellent yields with good functional group tolerance. C-H borylation was applied to the synthesis of a calcium receptor modulator.
Synthesis of pyridines from 1,2,4-triazines under high pressure
Krayushkin,Sedishev,Yarovenko,Zavarzin,Kotovskaya,Kozhevnikov,Charushin
, p. 407 - 411 (2008/12/22)
A procedure has been proposed for the synthesis of pyridines from 1,2,4-triazine derivatives and bicyclo[2.2.1]hepta-2,5-diene under high pressure in the presence of lithium perchlorate as catalyst.
Facile synthesis of 6-aryl-3-pyridyl-1,2,4-triazines as a key step toward highly fluorescent 5-substituted bipyridines and their Zn(II) and Ru(II) complexes
Kozhevnikov, Valery N.,Shabunina, Olga V.,Kopchuk, Dmitry S.,Ustinova, Maria M.,K?nig, Burkhard,Kozhevnikov, Dmitry N.
, p. 8963 - 8973 (2008/12/22)
A wide series of substituted bipyridines were obtained through the synthesis of 1,2,4-triazines and their aza Diels-Alder reactions. The reported method facilitates the synthesis of functionally diverse bipyridines that provides fine-tuning of photophysical properties of new ligands and their Zn(II) and Ru(II) complexes. Some of substituted bipyridines exhibit 'off-on' fluorescence response toward Zn2+ cations.
An efficient route to 5-(hetero)aryl-2,4′- and 2,2′-bipyridines through readily available 3-pyridyl-1,2,4-triazines
Kozhevnikov, Valery N.,Kozhevnikov, Dmitry N.,Shabunina, Olga V.,Rusinov, Vladimir L.,Chupakhin, Oleg N.
, p. 1791 - 1793 (2007/10/03)
A new route to substituted bipyridines based on a new method for the synthesis of substituted 3-pyridyl-1,2,4-triazines and their aza-Diels-Alder reactions is shown to be an efficient strategy for the preparation of structurally diverse bipyridine ligands.
