17399-20-1 Usage
Classification
Nitrophenylpropoxybenzene derivative This compound belongs to a group of derivatives characterized by the presence of a nitro group and a phenylpropoxy side chain attached to an aromatic ring.
Usage
Intermediate in pharmaceuticals and agrochemicals synthesis 1-nitro-3-(3-phenylpropoxy)benzene is primarily used as an intermediate in the production of various pharmaceuticals and agrochemicals.
Physical appearance
Yellow crystalline solid This organic compound has a yellow color and a crystalline structure.
Solubility
Insoluble in water, soluble in organic solvents 1-nitro-3-(3-phenylpropoxy)benzene does not dissolve in water but can dissolve in many organic solvents.
Hazard potential
Potentially hazardous chemical This compound is considered to be potentially hazardous, and appropriate safety precautions should be taken when handling it to minimize risks.
Check Digit Verification of cas no
The CAS Registry Mumber 17399-20-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,3,9 and 9 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17399-20:
(7*1)+(6*7)+(5*3)+(4*9)+(3*9)+(2*2)+(1*0)=131
131 % 10 = 1
So 17399-20-1 is a valid CAS Registry Number.
17399-20-1Relevant articles and documents
Design, synthesis, and anti-HCV activity of thiourea compounds
Kang, Iou-Jiun,Wang, Li-Wen,Lee, Chung-Chi,Lee, Yen-Chun,Chao, Yu-Sheng,Hsu, Tsu-An,Chern, Jyh-Haur
scheme or table, p. 1950 - 1955 (2009/11/30)
A series of thiourea derivatives were synthesized and their antiviral activity was evaluated in a cell-based HCV subgenomic replicon assay. SAR studies revealed that the chain length and the position of the alkyl linker largely influenced the in vitro anti-HCV activity of this class of potent antiviral agents. Among this series of compounds synthesized, the thiourea derivative with a six-carbon alkyl linker at the meta-position of the central phenyl ring (10) was identified as the most potent anti-HCV inhibitor (EC50 = 0.047 μM) with a selectivity index of 596.
Irreversible enzyme inhibitors. LXXXVII. Hydrophobic bonding to dihydrofolic reductase. IX. Mode of binding of m-aryloxyalkyl groups on 4,6-diamino-1,2-dihdro-2,2-dimethyl-1-phenyl-s-triazine.
Baker,Lourens
, p. 871 - 875 (2007/10/05)
-
