174-79-8

Usage

Uses

Used in Laboratory Applications:
2,6-Dioxaspiro[3.3]heptane is used as a solvent for its ability to dissolve various substances, facilitating numerous laboratory processes and reactions.
Used in Pharmaceutical Industry:
2,6-Dioxaspiro[3.3]heptane is used as a solvent in the pharmaceutical industry for its capacity to dissolve a broad spectrum of compounds, which aids in the formulation and development of various medications.
Used in Perfume Industry:
In the perfume industry, 2,6-Dioxaspiro[3.3]heptane is utilized as a solvent to dissolve fragrant compounds, contributing to the creation of diverse and complex scents.
Used in Organic Synthesis:
2,6-Dioxaspiro[3.3]heptane is employed as a reactant or intermediate in the synthesis of various organic compounds, playing a crucial role in the production of a range of chemical products.

InChI:InChI=1/C5H8O2/c1-5(2-6-1)3-7-4-5/h1-4H2

Upstream product

• 3296-90-0 bis(bromomethyl)bis(hydroxymethyl)methane 
• 2209-86-1 2,2-bis(chloromethyl)-1,3-propanediol 
• 64-17-5 ethanol 
• 1522-92-5 2,2-bis(bromomethyl)-3-bromo-propan-1-ol 
• 115-77-5 Pentaerythritol 
• 4351-77-3 3-(hydroxymethyl)-3-chloromethyl oxetane 

Downstream Products

• 89181-72-6 3,3-bis(nitratomethyl)oxetane 

Relevant academic research and scientific papers

Synthesis and properties of poly

The synthesis of poly has been performed in four steps.Chlorination of pentaerythritol produced a mixture of halogenated alcohols, which, in an alkaline medium, led to a mixture of hydroxylated and chlorinated oxetanes.Of these, the bis(3-chloromethyl) oxetane (BCMO) was etherified with C6F13C2H4OH via phase-transfer catalysis to yield the mono- and di-substituted fluorinated oxetanes.In a last step, the mono-substituted oxetane was cationically polymerized using BF3*OEt2 as the catalyst, and was characterized by 1H and 13C NMR spectroscopy.Finally, several physical properties have been determined such as the viscosity, glass transition and decomposition temperatures, and surface properties.

Chemical transformation of 3-bromo-2,2-bis(bromomethyl)-propanol under basic conditions

The mechanism of the spontaneous decomposition of 3-bromo-2,2- bis(bromomethyl)propanol (TBNPA) and the kinetics of the reaction of the parent compound and two subsequent products were determined in aqueous solution at temperatures from 30 to 70 °C and pH from 7.0 to 9.5. TBNPA is decomposed by a sequence of reactions that form 3,3-bis(bromomethyl)oxetane (BBMO), 3-bromomethyl-3-hydroxymethyloxetane (BMHMO), and 2,6-dioxaspiro[3.3]-heptane (DOH), releasing one bromide ion at each stage. The pseudo-first-order rate constant of the decomposition of TBNPA increases linearly with the pH. The apparent activation energy of this transformation (98 ± 2 KJ/mol) was calculated from the change of the effective second-order rate constant with temperature. The pseudoactivation energies of BBMO and BMHMO were estimated to be 109 and 151 KJ/mol, respectively. Good agreement was found between the rate coefficients derived from changes in the organic molecules concentrations and those determined from the changes in the Br- concentrations. TBNPA is the most abundant semivolatile organic pollutant in the aquitard studied, and together with its byproducts they posess an environmental hazard. TBNPA half-life is estimated to be about 100 years. This implies that high concentrations of TBNPA will persist in the aquifer long after the elimination of all its sources.

PREPARATION OF SOME SPIROCYCLIC OXETANES

Syntheses and spectroscopic properties of some oxetanes derived from pentaerythritol are discussed.