17401-27-3

Usage

Uses

3,4-Dihydro-9-phenyl-1(2H)-acridinone is used in the Friedlander synthesis of quinolines.

Upstream product

• 13047-06-8 o-bromobenzophenone 
• 504-02-9 1,3-cylohexanedione 
• 930-68-7 cyclohexenone 
• 2835-77-0 (2-aminophenyl)(phenyl)methanone 
• 108-94-1 cyclohexanone 

Relevant academic research and scientific papers

DMFDMA catalyzed synthesis of 2-((Dimethylamino)methylene)-3,4-dihydro-9-arylacridin-1(2H)-ones and their derivatives: In-vitro antifungal, antibacterial and antioxidant evaluations

A series of 3,4-dihydro-9-arylacridin-1(2H)-ones was synthesized and enaminone function was introduced at the C-2 position using DMFDMA catalyst which in turn successfully converted into pyrazole, isoxazol, 1-phenyl-1H-pyrazole by treating it with reagent

Green synthesis of trimetallic oxide nanoparticles and their use as an efficient catalyst for the green synthesis of quinoline and spirooxindoles: Antibacterial, cytotoxicity and anti-colon cancer effects

The three-metallic oxide (Cu/Cr/Ni) nanoparticles were prepared using Echinops persicus plant extract via a simple, biocompatible, cost-effective, and non-toxic procedure, and their catalytic activity was evaluated over the synthesis of biologically activ

Magnetic Fe–Cr–Ni oxide alloy nano-belts prepared from the chemical decomposition of a stainless steel screw (a top-down approach): an efficient and cheap catalyst for multicomponent reactions

Abstract: A new, cheap, and accessible method has been used for the preparation of nano-belts from the chemical decomposition (top-down approach) of a cheap stainless steel screw and found as an efficient magnetically recyclable nanocatalyst for the prepa

Synthesis of Fe3O4?SiO2/isoniazid/Cu(II) magnetic nanocatalyst as a recyclable catalyst for a highly efficient preparation of quinolines in moderate conditions

This paper reports the investigation on an efficient procedure to prepare Fe3O4?SiO2/isoniazid/Cu(II) as a recoverable magnetic nanocatalyst. The prepared nanocatalyst, Fe3O4?SiO2/isoniazid

A mild and efficient Ga(OTF)3-catalysed Friedl?nder reaction for the synthesis of quinolines

– The application of gallium triflate [Ga(OTf)3] for the synthesis of quinolines via the Friedl?nder reaction is described. This mild and straightforward method employed only 1 mol% of Ga(OTf)3 to deliver the quinoline products in excellent yields, demons

Effective and Sustainable Access to Quinolines and Acridines: A Heterogeneous Imidazolium Salt Mediates C–C and C–N Bond Formation

Quinoline and acridine derivatives have been prepared using a functionalized imidazolium salt as heterogeneous catalyst. Different ketones have been coupled with 2-aminobenzaldehydes and 2-aminoaryl ketones under solvent-free conditions, employing 1,3-bis(carboxymethyl)-imidazolium chloride as a catalyst. The protocol is simple and effective for the synthesis of a variety of nitrogen containing heterocycles (> 35 examples) with moderate to excellent yields (up to 96 %), being possible to perform the reaction in preparative scale. Additionally, 3-acetylquinolines have been transformed, under solvent-free conditions, into quinolyl chalcone derivatives by means of the same catalyst. Thus, the catalytic system mediates both reactions effectively in a tandem procedure. Furthermore, the catalyst is easily separated from the reaction mixture and can be reused without loss of activity (up to 8 cycles) which remarks its sturdiness. The E-factors are in the range of 14–23, both for the formation of quinolines and for the tandem reaction, which demonstrates the sustainability of the protocols described.

Ionic liquid as an efficient medium for the synthesis of quinoline derivatives via α-chymotrypsin-catalyzed friedl?nder condensation

An efficient, convenient, and eco-friendly biocatalytic approach was developed for the synthesis of quinoline derivatives via the α-chymotrypsin-catalyzed Friedl?nder reaction. Interestingly, α-chymotrypsin exhibited higher catalytic activity in an ionic