174020-29-2 Usage
Uses
Used in Research and Drug Development:
Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-3'-O-methylis utilized as a biochemical tool for investigating the structure and function of nucleic acids. Its unique chemical modifications allow researchers to probe the interactions between nucleic acids and other biomolecules, providing insights into the fundamental mechanisms of RNA biology and potential drug targets.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-3'-O-methylmay have potential therapeutic applications due to its ability to interact with nucleic acids and affect cellular processes. Its specific modifications could potentially be leveraged to develop new drugs targeting RNA-related diseases or conditions, although further research is needed to fully understand its pharmacological properties and potential therapeutic uses.
Used in Biochemical Research:
Uridine, 5'-O-[(4-methoxyphenyl)diphenylmethyl]-3'-O-methylis employed in biochemical research to study the interactions between nucleic acids and other biomolecules. Its unique chemical structure allows for the exploration of RNA-protein, RNA-RNA, and RNA-ligand interactions, contributing to a deeper understanding of RNA biology and its role in various cellular processes.
Check Digit Verification of cas no
The CAS Registry Mumber 174020-29-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,0,2 and 0 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 174020-29:
(8*1)+(7*7)+(6*4)+(5*0)+(4*2)+(3*0)+(2*2)+(1*9)=102
102 % 10 = 2
So 174020-29-2 is a valid CAS Registry Number.
174020-29-2Relevant academic research and scientific papers
176. Nucleosides part LXI: A simple procedure for the monomethylation of protected and unprotected ribonucleosides in the 2′-O- and 3′-O-position using diazomethane and the catalyst stannous chloride
Cramer, Hagen,Pfleiderer, Wolfgang
, p. 2114 - 2136 (2007/10/03)
Intensive studies on the diazomethane methylation of the common ribonucleosides uridine, cytidine, adenosine, and guanosine and its derivatives were performed to obtain preferentially the 2′-O-methyl isomers. Methylation of 5′-O-(monomethoxytrityl)-N 2-[2-(4-nitrophenyl)ethoxycarbonyl]-O 6-[2-(4-nitrophenyl)ethyl]-guanosine (1) with diazomethane resulted in an almost quantitative yield of the 2′-nd 3′-O-methyl isomers which could be separated by simple silica-gel flash chromatography (Scheme 1). Adenosine, cytidine, and uridine were methylated with diazomethane with and without protection of the 5′-O-position by a mono- or dimethoxytrityl group and the aglycone moiety of adenosine and cytidine by the 2-(4-nitrophenyl)ethoxycarbonyl (npeoc) group (Schemes 2-4). Attempts to increase the formation of the 2′-O-methyl isomer as much as possible were based upon various solvents, temperatures, catalysts, and concentration of the catalysts during the methylation reaction.
