17405-00-4

Usage

Uses

Used in Chemical Synthesis:
Benzenediazonium, 4-carboxy-, chloride is used as an intermediate in the synthesis of various organic compounds, particularly azo dyes. Its reactivity and functional groups make it a valuable precursor for the production of a wide range of dyes and pigments.
Used in Research Applications:
In the field of research, Benzenediazonium, 4-carboxy-, chloride is utilized for the study of diazonium chemistry and its applications in organic synthesis. It serves as a model compound for understanding the properties and reactions of diazonium salts, which are important in various chemical processes.
Used in Analytical Chemistry:
Benzenediazonium, 4-carboxy-, chloride can be employed in analytical chemistry for the detection and quantification of certain compounds. Its reactivity with specific reagents can be exploited to develop colorimetric or spectroscopic methods for the analysis of target substances.
Used in Pharmaceutical Industry:
Although not explicitly mentioned in the provided materials, Benzenediazonium, 4-carboxy-, chloride could potentially be used in the pharmaceutical industry as a building block for the synthesis of drug molecules. Its functional groups and reactivity may be harnessed to create novel compounds with therapeutic potential.

Upstream product

• 5351-17-7 4-aminobenzohydrazide 
• 1837-05-4 4-benzenediazonium-carboxylate 
• 110-46-3 isopentyl nitrite 
• 150-13-0 4-amino-benzoic acid 
• 102546-09-8 4-(2-anilino-[1]naphthylazo)-benzoic acid 

Downstream Products

• 67940-27-6 (E)-4-((8-hydroxyquinolin-5-yl)diazenyl)benzoic acid 
• 17995-09-4 4-(2-chloro-2-triethylsilanyl-ethyl)-benzoic acid 
• 10130-89-9 p-carboxyphenylsulfonyl chloride 
• 74-11-3 para-chlorobenzoic acid 
• 99-96-7 4-hydroxy-benzoic acid 
• 108128-50-3 (4-carboxy-phenylazomercapto)-acetic acid 
• 28764-81-0 4-benzenesulfonylazo-benzoic acid 
• 36893-27-3 α-Bromglyoxal-p-carboxyphenylhydrazon 
• 129841-49-2 4-(2-Hydroxy-3,4-dioxo-cyclobut-1-enyl)-benzoic acid 
• 82587-81-3 4-{N'-[6-Methyl-4-oxo-7,8-dihydro-4H,6H-pyrido[1,2-a]pyrimidin-(9Z)-ylidene]-hydrazino}-benzoic acid 
• 6652-57-9 4-Carboxy-phenylhydrazon-bis-phenylsulfonyl-formaldehyd 
• 619-58-9 4-iodobenzoic acid 
• 619-65-8 4-cyanobenzoic Acid 
• 586-91-4 azobenzene-4,4'-dicarboxylic acid 

Relevant academic research and scientific papers

Photoresponsive behavior of two well-defined azo polymers with different electron-withdrawing groups on push-pull azo chromophores

Two well-defined methacrylate-based azo polymers bearing strong push-pull azo chromophores were synthesized by RAFT polymerization. The polymers contain cyano and carboxyl as electron-withdrawing groups at 4-positions of the azo chromophores. The polymers

Synthesis, characterization and properties of a novel environmentally friendly mono azo disperse dye and its application on polyethylene terephthalate (PET)

The aim of this research is to achieve the synthesis of a novel mono azo disperse dye containing both a β- naphthyl acetate group and carboxylic acid ester group and application on PET fabric. In this study the dyeing properties have also been investigate

Experimental and theoretical studies of azo derivatives in terms of different donors, acceptors and position isomerism: Synthesis, characterization and a combined electronic absorption, electrochemical and DFT study

Eight azo derivatives with two donor groups- diphenylamine and N,N-dimethylphenyl, and four acceptor groups - 3-nitrophenyl, 4-nitrophenyl, 4-phenylcarboxylic acid, and 3-phenylcarboxylic acid, were synthesized and characterized using 1H-NMR an

Design, synthesis and biological evaluation of small-azo-dyes as potent Vesicular Glutamate Transporters inhibitors

Vesicular Glutamate Transporters (VGLUTs) allow the loading of presynapic glutamate vesicles and thus play a critical role in glutamatergic synaptic transmission. VGLUTs have proved to be involved in several major neuropathologies and directly correlated to clinical dementia in Alzheimer and Parkinson's disease. Accordingly VGLUT represent a key biological target or biomarker for neuropathology treatment or diagnostic. Yet, despite the pivotal role of VGLUTs, their pharmacology appears quite limited. Known competitive inhibitors are restricted to some dyes as Trypan Blue (TB) and glutamate mimics. This lack of pharmacological tools has heavily hampered VGLUT investigations. Here we report a rapid access to small molecules that combine benefits of TB and dicarboxylic quinolines (DCQs). Their ability to block vesicular glutamate uptake was evaluated. Several compounds displayed low micromolar inhibitory potency when size related compounds are thirty to forty times less potent (i.e. DCQ). We then confirmed the VGLUT selectivity by measuring the effect of the series on vesicular monoamine transport and on metabotropic glutamate receptor activity. These inhibitors are synthesized in only two steps and count among the best pharmacological tools for VGLUTs studies.

Waste-free chemistry of diazonium salts and benign separation of coupling products in solid salt reactions

Gas-solid and solid-solid techniques allow for waste-free and quantitative syntheses in the chemistry of diazonium salts. Five techniques for diazotations with the reactive gases NO2, NO and NOCl are studied. Two types are mechanistically investigated with atomic force microscopy (AFM) and are interpreted on the basis of known crystal packings. The same principles apply to the cascade reactions that had been derived from one-step reactions. Solid diazonium salts couple quantitatively with solid diphenylamine and anilines to give the triazenes. Azo couplings are achieved with quantitative yields by cautious co-grinding of solid diazonium salts with β-naphthol and C-H acidic heterocycles, such as barbituric acids or pyrazolinones. Solid diazonium salts may be more easily applied in a stoichiometric ratio for couplings in solution. Co-grinding of solid diazonium salts with KI gives quantitative yields of various solid aryl iodides. The unavoidable coupling products in salt reactions are completely separated from the insoluble products in a highly benign manner. The solid-state reactions compare favourably with similar solution reactions that produce much waste. The structures of the products are elucidated with IR and NMR spectroscopy and mass spectrometry, while the tautomeric properties of the compounds are studied with density functional calculations at the B3LYP/6-31G* and BLYP/6-31G** levels.

Aromatic and Azaaromatic Diselenides, Benzisoselenazolones and Related Compounds as Immunomodulators Active in Humans: Synthesis and Properties

Convenient syntheses of aryl diselenides 2, 1,2-benzisoselenazol-3(2H)-ones 4 and their 1-oxides 7 are reported.Reductive conversions of these compounds to bis(2-carbamoyl)phenyl diselenides 5 and oxidative cyclization of 5 to 1,2-benzisoselenazol-3(2H)-one 1-oxides 7 as the methods for the synthesis of these compounds are reported.Their ability to induce cytokines, such as TNF and IFN-γ, in human peripheral blood leucocyte cultures is described. - Key Words: 1,2-benzisoselenazol-3(2H)-ones/ Cytokine inducers/ Diselenides/ Interferon-gamma/ Tumor necrosis factor

Syntheses and NMR Behavior of Calixquinone and Calixhydroquinone

Calixquinone (7) and calixhydroquinone (6) have been synthesized using three different synthetic pathways.The first pathway to 7 from calixarene (1) consists of six steps: acetylation, Fries rearrangement, Baeyer-Villiger oxidation after acetylat

Polarography of Some Arylazothiohydantoin Derivatives

The polarographic behaviour of a series of arylazothiohydantoin derivatives has been investigated at a dropping mercury electrode.Two wawes were displayed.The first and predominant one is due to the reductive splitting of the azo-linkage by a 4e irreversi