174064-00-7Relevant articles and documents
[3,3]-Sigmatropic Rearrangements in the Enantioselective Synthesis of (-)-Methylenolactocin
Ariza, Xavier,Fernández, Natalia,Garcia, Jordi,López, Marta,Montserrat, Laia,Ortiz, Jordi
, p. 128 - 134 (2004)
A Pd(II)-catalyzed [3,3]-sigmatropic rearrangement is used to transfer chirality from an enantio-enriched alk-3-ene-1,2-diol to a C2- symmetrical alk-2-ene-1,4-diol which, in turn, can be converted into a precursor of (-)-methylenolactocin through an additional [3,3]-sigmatropic rearrangement (either Johnson orthoester or Ireland-Claisen rearrangement).
Unsaturated syn - And anti -1,2-amino alcohols by cyclization of allylic bis-trichloroacetimidates. Stereoselectivity dependence on substrate configuration
Grigorjeva, Liene,Kinens, Artis,Jirgensons, Aigars
, p. 920 - 927 (2015)
Disubstituted allylic bis-imidates undergo Lewis acid catalyzed or spontaneous cyclization to oxazolines, which are precursors of unsaturated amino alcohols. Stereoselectivity of the cyclization is mainly determined by the substrate configuration. Highly