174088-55-2

Upstream product

• 144944-85-4 2',5'-di-O-acetyl-3'-deoxy-3'-C-(2-hydroxyethyl)-2-O-para-methoxyphenyl-(β-D-ribofuranosyl)thymine 
• 87-65-0 2,6-Dichlorophenol 
• 174088-54-1 Acetic acid (2R,3R,4R,5S)-5-acetoxymethyl-2-[4-(2,6-dichloro-phenoxy)-5-methyl-2-oxo-2H-pyrimidin-1-yl]-4-[2-(4-methoxy-phenoxy)-ethyl]-tetrahydro-furan-3-yl ester 

Downstream Products

• 174088-84-7 C₄₄H₅₀N₄O₁₂S 
• 174088-52-9 C₄₄H₅₀N₄O₁₁S 
• 174088-61-0 C₃₉H₅₀N₄O₉SSi 
• 174088-57-4 1-{(2R,3R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methoxy-4-[2-(4-methoxy-phenoxy)-ethyl]-tetrahydro-furan-2-yl}-4-(2,6-dichloro-phenoxy)-5-methyl-1H-pyrimidin-2-one 
• 174088-58-5 1-{(2R,3R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-3-methoxy-4-[2-(4-methoxy-phenoxy)-ethyl]-tetrahydro-furan-2-yl}-5-methyl-1H-pyrimidine-2,4-dione 
• 174088-60-9 Methanesulfonic acid 2-[(2S,3R,4R,5R)-2-(tert-butyl-diphenyl-silanyloxymethyl)-4-methoxy-5-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl]-ethyl ester 
• 174088-59-6 1-[(2R,3R,4R,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-4-(2-hydroxy-ethyl)-3-methoxy-tetrahydro-furan-2-yl]-5-methyl-1H-pyrimidine-2,4-dione 

Relevant academic research and scientific papers

Synthesis of 2'-substituted sulfide-linked dinucleotides

3'-Deoxy-3'-(2-mesyloxyethyl)ribofuranosylthymine derivative 3, and its 2'-methoxy (16) and 2'-deoxy (38) analogs were condensed with 5'-deoxy-5'- thiothymidine 4 and 17 or 2'-O-methyl-5'-deoxy-5'-thiouridine 34 and 37 to provide, after standard functional group transformations, thymidine-thymidine and uridine-thymidine dimers 9, 21, 43 and 47. Oxidation of model sulfide dimer 48 with oxone gave sulfone 49. It was not stable to 27% ammonia.