174096-53-8

Upstream product

• 132835-12-2 Acetic acid (2R,3S)-3-hydroxymethyl-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester 
• 174096-66-3 Acetic acid (2R,3S)-3-(2-ethoxy-ethoxymethyl)-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester 

Downstream Products

• 152897-55-7 (3S,4S)-5-tert-butyldiphenylsilyloxy-3-hydroxy-4-(N-tosylamino)pentanenitrile 
• 152897-49-9 (2R,3S)-2-tert-butyldiphenylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine 
• 152897-54-6 (R)-2-<(R)-2-tert-butyldiphenylsilyloxy-1-(N-tosylamino)ethyl>oxirane 
• 174096-63-0 (3S,4S)-3-hydroxy-5-tosyloxy-4-(N-tosylamino)pentanenitrile 
• 174096-65-2 (3S,4S)-3-hydroxy-5-phenyl-4-(N-tosylamino)pentanoic acid 
• 152897-56-8 (3S,4S)-3-hydroxy-5-phenyl-4-(N-tosylamino)pentanenitrile 
• 174096-64-1 (3S,4R)-3-hydroxy-5-iodo-4-(N-tosylamino)pentanenitrile 
• 174096-62-9 (3S,4S)-3,5-dihydroxy-4-(N-tosylamino)pentanenitrile 
• 174096-54-9 (2R,3S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(2-ethoxy-ethoxymethyl)-1-(toluene-4-sulfonyl)-aziridine 

Relevant academic research and scientific papers

An enantiodivergent synthesis of three β-amino alcohols: Preparation of key intermediates for bestatin and the related peptides

An enantiodivergent method for preparation of three β-amino alcohols and three 1,2-diamines has been developed starting with a chiral aziridine 1. Unusual amino acid derivatives 3 and 5, which are key synthetic intermediates for bestatin and the related peptides, have been prepared.