174096-65-2

Upstream product

• 174096-54-9 (2R,3S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-3-(2-ethoxy-ethoxymethyl)-1-(toluene-4-sulfonyl)-aziridine 
• 174096-66-3 Acetic acid (2R,3S)-3-(2-ethoxy-ethoxymethyl)-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester 
• 174096-53-8 [(2R,3S)-3-(2-Ethoxy-ethoxymethyl)-1-(toluene-4-sulfonyl)-aziridin-2-yl]-methanol 
• 23402-69-9 lithium diphenylcuprate 
• 132835-12-2 Acetic acid (2R,3S)-3-hydroxymethyl-1-(toluene-4-sulfonyl)-aziridin-2-ylmethyl ester 
• 152897-55-7 (3S,4S)-5-tert-butyldiphenylsilyloxy-3-hydroxy-4-(N-tosylamino)pentanenitrile 
• 152897-49-9 (2R,3S)-2-tert-butyldiphenylsilyloxymethyl-3-hydroxymethyl-N-tosylaziridine 
• 152897-54-6 (R)-2-<(R)-2-tert-butyldiphenylsilyloxy-1-(N-tosylamino)ethyl>oxirane 
• 174096-63-0 (3S,4S)-3-hydroxy-5-tosyloxy-4-(N-tosylamino)pentanenitrile 
• 174096-64-1 (3S,4R)-3-hydroxy-5-iodo-4-(N-tosylamino)pentanenitrile 
• 174096-62-9 (3S,4S)-3,5-dihydroxy-4-(N-tosylamino)pentanenitrile 

Downstream Products

• 72155-48-7 (3S,4S)-4-tert-butoxycarbonylamino-3-hydroxy-5-phenylpentanoic acid 
• 72155-50-1 (3S,4S)-4-amino-3-hydroxy-5-phenylpentanoic acid 

Relevant academic research and scientific papers

Ring opening of optically active cis-disubstituted aziridino alcohols: An enantiodivergent synthesis of functionalized amino alcohol derivatives

Ring-opening reactions of optically active cis-disubstituted aziridino alcohols have been investigated. Regio- and stereo-selective ring opening took place with internal and external nucleophiles. Unusual amino acids derivatives (14) and (15), the key synthetic intermediates for bestatin and related peptides, have been prepared. n.

An enantiodivergent synthesis of three β-amino alcohols: Preparation of key intermediates for bestatin and the related peptides

An enantiodivergent method for preparation of three β-amino alcohols and three 1,2-diamines has been developed starting with a chiral aziridine 1. Unusual amino acid derivatives 3 and 5, which are key synthetic intermediates for bestatin and the related peptides, have been prepared.