174149-70-3

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 174149-69-0 (3aR,3bR,6aR,7S,7aR)-7-hydroxy-2,2-dimethyl<1,3>dioxolo<4,5-d>cyclopent<4,5-d>oxazolidin-5-one 
• 56745-67-6 (4S)-4-tert-butyldimethylsilyloxycyclopent-2-en-1-one 
• 120520-91-4 (1R,4S)-4-(tert-butyldimethylsilyloxy)cyclopent-2-enol 
• 174149-60-1 (1R,2S,3S,4S)-4-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-64-5 (1S,2S,3S,4S,5R)-3-O-(tert-butyldimethylsilyl)-5-iodo-1,2-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-62-3 (1S,2S,3S)-3-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidenecyclopent-4-ene-1,2,3-triol 
• 174149-57-6 (1R,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)cyclopent-2-ene-1,4-diol 
• 174149-58-7 (1R,2R,3S,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)cyclopentane-1,2,3,4-tetrol 
• 174149-68-9 (1S,2R,3S,4R,5S)-5-((tert-butoxycarbonyl)amino)-1,2-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-65-6 (1R,2R,3R,4S,5S)-3,4-bis-O-(tert-butyldimethylsilyl)-5-iodo-1,2-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-59-8 (1R,2S,3S,4S)-1-O-benzyl-4-O-(tert-butyldimethylsilyl)-2,3-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-63-4 (1S,2S,3R,4S,5S)-4-O-acetyl-3-O-(tert-butyldimethylsilyl)-5-iodo-2,3-O-isopropylidenecyclopentane-1,2,3,4-tetrol 
• 174149-66-7 (1S,2S,3R,4R,5R)-5-azido-3,4-bis-O-(tert-butyldimethylsilyl)-1,2-O-isopropylidenecyclopentane-1,2,3,4-tetrol 

Downstream Products

• 174149-71-4 (3aR,4S,5S,6R,6aR)-6-((benzyloxy)methoxy)-4,5-dihydroxycyclopentoxazolidin-2-one 

Relevant academic research and scientific papers

Flexible enantiodivergent synthesis and biological activity of mannostatin analogues, new cyclitol glycosidase inhibitors

Mannostatin A (1) is a new cyclitol inhibitor of glycoprotein processing. 2-Epimannostatin A (12) and its enantiomer (13) as well as their positional isomers (14, 15) were designed for probing structure-activity relationships in this class of glycosidase inhibitors. The analogues have been synthesized from (S)-4-((tert-butyldimethylsilyl)oxy)-2-cyclopentenone by an enantiodivergent strategy in a totally stereospecific fashion. Compound 13 showed inhibition against almond β-glucosidase and is shown to be a topographical analogue of β-D-glucopyranoside.