56745-67-6

Basic information

• Product Name: 2-Cyclopenten-1-one, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-
• Synonyms: 4-[tert-Butyl(dimethyl)silyl]oxycyclopent-2-en-1-one
• CAS NO: 56745-67-6
• Molecular Formula: C₁₁H₂₀O₂Si
• Molecular Weight: 212.364
• Mol File: 56745-67-6.mol

Chemical Properties

• Boiling Point: 246.128 °C at 760 mmHg
• Flash Point: 85.393 °C
• Density: 0.944 g/cm³
• CAS DataBase Reference: 2-Cyclopenten-1-one, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Cyclopenten-1-one, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-(56745-67-6)
• EPA Substance Registry System: 2-Cyclopenten-1-one, 4-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-(56745-67-6)

Safety Data

• Hazardous Substances Data: 56745-67-6(Hazardous Substances Data)

Upstream product

• 69739-34-0 t-butyldimethylsiyl triflate 
• 59995-47-0 4-Hydroxycyclopent-2-enone 
• 61305-35-9 4-[(tert-butyldimethylsilyl)oxy]cyclopent-2-enone 
• 98-80-6 phenylboronic acid 
• 1391630-27-5 (+/-)-4-oxocyclopenten-2-enyl 2-phenylacetate 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Downstream Products

• 114738-33-9 (1S^*,3R^*,4S^*)-1-acetoxy-3-<(tert-butyldimethylsilyl)oxy>-4-phenylcyclopentane 
• 114738-39-5 1-hydroperoxy-3-phenylcyclopent-2-ene 
• 114738-38-4 1-hydroperoxy-3-phenylcyclopent-3-ene 
• 1384870-76-1 4-(tert-butyldimethylsilyloxy)-2-((tert-butyldiphenylsilyloxy)methyl)cyclopent-2-enone 
• 1416429-78-1 C₁₇H₂₄O₂SeSi 
• 61305-35-9 (R)-4-((tert-butyldimethylsilyl)oxy)cyclopent-2-enone 
• 56745-67-6 (4S)-4-tert-butyldimethylsilyloxycyclopent-2-en-1-one 
• 59995-48-1 (R)-4-acetoxycyclopent-2-en-1-one 
• 61305-30-4 (R)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (1R,4S)-4-(tert-butyl-dimethyl-silanyloxy)-cyclopent-2-enyl ester 

Relevant articles and documents

Pseudo enantiomeric carbohydrate olefin ligands - Case study and application in kinetic resolution in rhodium(I)-catalysed 1,4-addition

In order to investigate significant differences in asymmetric induction for pseudo enantiomeric carbohydrate olefin ligands in rhodium(I)-catalysed 1,4-addition reactions, we designed a set of new olefin ligands differing in relative configuration and pyranoside conformation. With these, we have successfully elucidated structural requirements for metal binding and also identified an improved alternative for one pseudo enantiomer. Furthermore, we report the efficient kinetic resolution of a racemic 4-hydroxycyclopentenone derivative by 1,4-addition.

Resolution of racemic 4-hydroxy-2-cyclopentenone with immobilized penicillin G acylase

Enantiomerically pure 4-oxo-2-cyclopentenyl derivatives were prepared by kinetic resolution with penicillin G acylase (EC 3.5.1.11) immobilized on an epoxy activated polymer. The enzyme selectively hydrolyzes the phenylacetyl ester of the (S)-enantiomer t