17419-82-8

Basic information

• Product Name: trans-4-Hydroxy-cyclohexanecarboxylic acid hydrazide
• Synonyms: trans-4-Hydroxy-cyclohexanecarboxylic acid hydrazide
• CAS NO: 17419-82-8
• Molecular Weight: 158.2
• Mol File: 17419-82-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: trans-4-Hydroxy-cyclohexanecarboxylic acid hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: trans-4-Hydroxy-cyclohexanecarboxylic acid hydrazide(17419-82-8)
• EPA Substance Registry System: trans-4-Hydroxy-cyclohexanecarboxylic acid hydrazide(17419-82-8)

Safety Data

• Hazardous Substances Data: 17419-82-8(Hazardous Substances Data)

Upstream product

• 3618-04-0 4-hydroxycyclohexyl carboxylic acid ethyl ester 
• 3685-26-5 trans-4-hydroxycyclohexanecarboxylic acid 

Downstream Products

• 1337966-02-5 8-chloro-1-(4-oxo-cyclohexyl)-4H,6H-2,3,5,10b-tetraazabenzo[e]azulene-5-carboxylic acid tert-butyl ester 
• 1337966-03-6 8-Chloro-1-(4-hydroxy-4-o-tolyl-cyclohexyl)-4H,6H-2,3,5,10b-tetraaza-benzo[e]azulene-5-carboxylic acid tert-butyl ester 
• 1339126-76-9 8-chloro-1-(4-hydroxy-4-phenylcyclohexyl)-4H,6H-2,3,5,10b-tetraazabenzo[e]azulene-5-carboxylic acid tert-butyl ester 
• 1337966-01-4 cis/trans-8-chloro-1-(4-hydroxycyclohexyl)-4H,6H-2,3,5,10b-tetraazabenzo[e]azulene-5-carboxylic acid tert-butyl ester 
• 27489-62-9 trans-4-hydroxycyclohexylamine 
• 71118-96-2 trans-4-Aethoxycarbonylamino-cyclohexanol 

Relevant articles and documents

ARYL-/HETEROARYL-CYCLOHEXENYL-TETRAAZABENZO[E]AZULENES

The present invention is concerned with aryl-/heteroaryl-cyclohexenyl-tetraazabenzo[e]azulenes of formula I wherein R1, R2 and R3 are as described herein. The invention further provides methods for the manufacture of such compounds and pharmaceutical compositions containing them. The compounds according to the invention act as V1a receptor modulators, and in particular as V1a receptor antagonists, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful as therapeutics acting peripherally and centrally in the conditions of dysmenorrhea, male or female sexual dysfunction, hypertension, chronic heart failure, in appropriate secretion of vasopressin, liver cirrhosis, nephrotic syndrome, anxiety, depressive disorders, obsessive compulsive disorder, autistic spectrum disorders, schizophrenia, and aggressive behavior.

Heterocyclic inhibitors of 11-beta hydroxyl steroid dehydrogenase type 1 and methods of using the same

The present invention relates to inhibitors of 11-β hydroxyl steroid dehydrogenase type 1 and pharmaceutical compositions thereof. The compounds of the invention can be useful in the treatment of various diseases associated with expression or activity of