3685-26-5Relevant articles and documents
A Molecular Torsion Balance Study: A Nearby Anionic Group Exerts Little Influence on Hydrophobic Interactions between Nonpolar Surfaces
Ling, Xiujun,Wilcox, Craig S.
supporting information, p. 14010 - 14014 (2019/11/14)
Polar groups have a solvent ordering effect on water and therefore may affect hydrophobic binding energies for nearby lipophilic surfaces. This would mean that determinations of excess surface free energy association energies require consideration of nearby polar functional groups. This paper reports results of a study to measure this possible effect. It was concluded from the models used here that an anionic polar group nearby a hydrophobic surface has little or no effect on the magnitude of hydrophobic association.
Preparing method for trans- 4- hydroxycyclohexanecarboxylic acid
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Paragraph 0008-0010, (2017/08/27)
The invention discloses a preparing method for trans- 4- hydroxycyclohexanecarboxylic acid. The method comprises the steps of adding p-hydroxybenzoic acid, catalyst and solvent into the high pressure reactor to obtain cis- and trans- 4-hydroxycyclohexanecarboxylic acid, then adding the 4-hydroxycyclohexanecarboxylic acid into the solvent and adding a certain volume of sodium alkoxide as the catalyst, increasing the temperature and obtain trans- 4- hydroxycyclohexanecarboxylic acid with content of over 90% through isomerization reaction. Then obtaining pure trans- 4- isomerization reaction by recrystallization of petroleum ether ethyl acetate. Benefit of the invention: the invention provides a preparing method for trans- 4- hydroxycyclohexanecarboxylic acid. The raw material is easy to obtain and the product can be produced in large scale, which greatly reduces the cost.
A method for synthesizing metabolite pqt (by machine translation)
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Paragraph 0029; 0031, (2017/01/02)
The invention relates to two kinds of pqt of the synthetic method of metabolic product, belongs to the technical field of medicament, are respectively to pqt and 4 the hydroxy [...] cyclohexane carboxylic acid methyl ester as the raw material, pqt and cyclohexenols -3 the [...] formic acid as the raw material to synthesize the pqt two metabolic product. The advantages of: the invention the first time the two portions metabolic product. And, these two kinds of pqt metabolic product of simple synthesis technology, high purity of the product. (by machine translation)