174198-33-5Relevant academic research and scientific papers
Facile synthesis of pyrazino[2,3-e][1,4]diazepine derivatives via the intramolecular aza-Wittig reaction
Okawa, Tomohiro,Eguchi, Shoji
, p. 81 - 84 (1996)
Pyrazino[2,3-d][1,4]diazepine derivatives were synthesized from 3-aminopyrazine-2-carboxylic acid 1 and α-amino acid esters via the intramolecular aza-Wittig reaction.
Synthesis of pyrazino[2,3-e] [1,4]diazepin-5-one and pyrazino[2,3- e]pyrrolo[1,2-a][1,4]diazepin-5-one derivatives via the intramolecular aza- Wittig reaction
Okawa, Tomohiro,Eguchi, Shoji
, p. 5853 - 5868 (2007/10/03)
2-Alkoxy pyrazino[2,3-e][1,4]diazepin-5-one and 11-alkoxy pyrazino[2,3- e]pyrrolo[1,2-a][1,4]diazepin-5-one derivatives were synthesized via the corresponding iminophosphoranes derived from 3-aminopyrazine-2-carboxylic acid and α-amino acid derivatives, by the intramolecular aza-Wittig methodology. (11S, 11aS)-1,2,3,10,11,11a-Hexahydro-11-alkoxy-pyrazino[2,3- e]pyrrolo[1,2-a][1,4]diazepin-5-one derivatives, i.e., 6,9-diaza-analogs of porothramycin B etc., were obtained.
