174198-75-5

Upstream product

• 100-39-0 benzyl bromide 
• 174198-74-4 (2R,3S,6S)-2-(tert-Butyl-diphenyl-silanyloxymethyl)-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-3-ol 
• 35334-60-2 (E)-6-acetoxy-4-methyl-4-hexenal 
• 174198-56-2 Benzoic acid (E)-(S)-1-((R)-1,2-dihydroxy-ethyl)-4-methyl-6-(tetrahydro-pyran-2-yloxy)-hex-4-enyl ester 
• 174198-57-3 Benzoic acid (E)-(S)-1-((R)-1,2-dihydroxy-ethyl)-6-hydroxy-4-methyl-hex-4-enyl ester 
• 174198-58-4 Benzoic acid (2R,3S,6S)-6-((R)-1,2-dihydroxy-ethyl)-2-hydroxymethyl-6-methyl-tetrahydro-pyran-3-yl ester 
• 174198-55-1 {(2R,3R)-3-[(E)-3-Methyl-5-(tetrahydro-pyran-2-yloxy)-pent-3-enyl]-oxiranyl}-methanol 
• 174198-54-0 (2E,6E)-6-Methyl-8-(tetrahydro-pyran-2-yloxy)-octa-2,6-dien-1-ol 
• 174198-73-3 (2R,3S,6S)-6-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-2-hydroxymethyl-6-methyl-tetrahydro-pyran-3-ol 
• 110965-84-9 (2E,6E)-methyl-8-acetoxy-6-methylocta-2,6-dienoate 
• 110965-85-0 (2E,6E)-8-Hydroxy-6-methyl-octa-2,6-dienoic acid methyl ester 

Downstream Products

• 174198-64-2 (E)-5-[(2R,3S,6S)-6-((R)-2-Acetoxy-1-methanesulfonyloxy-ethyl)-3-benzyloxy-6-methyl-tetrahydro-pyran-2-yl]-3-methyl-pent-2-enoic acid ethyl ester 
• 174198-79-9 (E)-5-[(2R,3S,6S)-6-((R)-2-Acetoxy-1-hydroxy-ethyl)-3-benzyloxy-6-methyl-tetrahydro-pyran-2-yl]-3-methyl-pent-2-enoic acid ethyl ester 
• 174198-61-9 Acetic acid (R)-2-((2S,5S,6R)-5-benzyloxy-6-but-3-enyl-2-methyl-tetrahydro-pyran-2-yl)-2-methanesulfonyloxy-ethyl ester 
• 174198-67-5 ((2S,3S)-3-{2-[(2R,3S,6S)-3-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-2-yl]-ethyl}-3-methyl-oxiranyl)-methanol 
• 174198-63-1 (E)-5-[(2R,3S,6S)-3-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-2-yl]-3-methyl-pent-2-enoic acid ethyl ester 
• 174198-81-3 (E)-5-[(2R,3S,6S)-3-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-2-yl]-3-methyl-pent-2-en-1-ol 
• 174198-78-8 (E)-5-[(2R,3S,6S)-3-Benzyloxy-6-((R)-1,2-dihydroxy-ethyl)-6-methyl-tetrahydro-pyran-2-yl]-3-methyl-pent-2-enoic acid ethyl ester 
• 174198-62-0 4-[(2R,3S,6S)-3-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-2-yl]-butan-2-one 
• 174198-77-7 Acetic acid (R)-2-((2S,5S,6R)-5-benzyloxy-6-but-3-enyl-2-methyl-tetrahydro-pyran-2-yl)-2-hydroxy-ethyl ester 
• 174198-60-8 (2S,5S,6R)-5-Benzyloxy-6-but-3-enyl-2-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-2-methyl-tetrahydro-pyran 
• 174198-76-6 (R)-1-((2S,5S,6R)-5-Benzyloxy-6-but-3-enyl-2-methyl-tetrahydro-pyran-2-yl)-ethane-1,2-diol 
• 174198-59-5 [(2R,3S,6S)-3-Benzyloxy-6-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-6-methyl-tetrahydro-pyran-2-yl]-methanol 

Relevant academic research and scientific papers

Stereoselective synthesis of the C-and CD-ring systems of hemibrevetoxin B

The 7, 7-membered CD ring system of hemibrevetoxin B was stereoselectively synthesized. The crucial steps involve the Sharpless asymmetric epoxidation, cyclization to the 6-membered ether, and double rearrangement of the 6, 6-membered bicyclic ether with