17426-48-1Relevant academic research and scientific papers
On the base-induced isomerization of cyclic propargylamides to cyclic allenamides
Fenández, Israel,Monterde, María I.,Plumet, Joaquín
, p. 6029 - 6031 (2007/10/03)
The reaction of lactams 4 (n = 1-5) with propargyl bromide affords propargylamides or allenylamides depending on the ring-size. Theoretical calculations support the dependence of the extension of the isomerization on the ring-size.
