174264-48-3 Usage
Uses
Used in Pharmaceutical Industry:
Methyl-1-(6-tert-butyldimethylsylyl-4’-hydroxyraloxifene)-2,3,4-tri-O-acetyl--D-glycopyranuronate is used as an intermediate in the synthesis of Raloxifene metabolites for the development of pharmaceutical drugs. The application reason is its role in creating a nonsteroidal estrogen receptor mixed agonist/antagonist, which can be used to treat conditions related to estrogen receptor activity, such as osteoporosis and certain types of cancer.
Used in Synthesis of Raloxifene Metabolites:
Methyl-1-(6-tert-butyldimethylsylyl-4’-hydroxyraloxifene)-2,3,4-tri-O-acetyl--D-glycopyranuronate is used as a key component in the synthesis process of Raloxifene metabolites. The application reason is its ability to facilitate the creation of a compound with mixed agonist/antagonist properties, which can be beneficial in the treatment of various medical conditions.
Chemical Properties:
The chemical properties of Methyl-1-(6-tert-butyldimethylsylyl-4’-hydroxyraloxifene)-2,3,4-tri-O-acetyl--D-glycopyranuronate include its orange foam appearance, which may be indicative of its unique structural and functional characteristics. This property could be relevant in the identification, handling, and further processing of the compound in the context of pharmaceutical research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 174264-48-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,4,2,6 and 4 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 174264-48:
(8*1)+(7*7)+(6*4)+(5*2)+(4*6)+(3*4)+(2*4)+(1*8)=143
143 % 10 = 3
So 174264-48-3 is a valid CAS Registry Number.
174264-48-3Relevant academic research and scientific papers
Synthesis and estrogen receptor binding affinities of the major human metabolites of raloxifene (LY139481)
Dodge, Jeffrey A.,Lugar, Charles W.,Cho, Stephen,Osborne, John J.,Phillips, David L.,Glasebrook, Andrew L.,Frolik, Charles A.
, p. 993 - 996 (2007/10/03)
Glucuronide conjugates 1 and 2, the major metabolites of raloxifene, have been prepared and their molecular interactions with the estrogen receptor determined.
