1743-96-0

Basic information

• Product Name: Benzene, 1-nitro-4-(pentafluoroethoxy)-
• Synonyms: Benzene, 1-nitro-4-(pentafluoroethoxy)-;1-Nitro-4-(perfluoroethoxy)benzene
• CAS NO: 1743-96-0
• Molecular Formula: C₈H₄F₅NO₃
• Molecular Weight: 257.114276
• EINECS: -0
• Mol File: 1743-96-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: Benzene, 1-nitro-4-(pentafluoroethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-nitro-4-(pentafluoroethoxy)-(1743-96-0)
• EPA Substance Registry System: Benzene, 1-nitro-4-(pentafluoroethoxy)-(1743-96-0)

Safety Data

• Hazardous Substances Data: 1743-96-0(Hazardous Substances Data)

Usage

General Description

Benzene, 1-nitro-4-(pentafluoroethoxy)- is a chemical compound with the molecular formula C8H4F5NO3. It is a nitro compound with a pentafluoroethoxy group attached to the benzene ring. Benzene, 1-nitro-4-(pentafluoroethoxy)- is used in the synthesis of various pharmaceuticals, pesticides, and other organic compounds. It is a colorless, flammable liquid with a floral, fruity odor. It is considered to be a potential environmental pollutant and is primarily used as an intermediate in the production of other chemicals. It is important to handle this compound with care due to its flammability and potential toxicity.

Upstream product

• 658-78-6 1-nitro-4-trifluoroacetoxy-benzene 
• 100-02-7 4-nitro-phenol 

Downstream Products

• 98-16-8 3-trifluoromethylaniline 

Relevant articles and documents

2-Trifluoromethyl-1,3-dithianylium triflate: A convenient 'masked' electrophilic pentafluoroethylation reagent

With 2-trifluoromethyl-1,3-dithianylium triflate for the first time the synthesis, isolation and full structural characterization of an α-perfluoroalkylcarbenium salt was achieved. The title compound can be easily obtained on a preparative scale. The thermally stable dithianylium salt in combination with fluorodesulfurization chemistry is a promising novel reagent for the electrophilic polyfluoroalkylation of organic substrates, demonstrated by the pentafluoroethylation of O-nucleophiles.

FLUORINATION PROCESS

It has been found that a compound of formula (I) R-CF2-O-Ar, wherein R is a fluorinated alkyl group or an optionally substituted aromatic or heteroaromatic group and Ar is an optionally substituted aromatic or heteroaromatic group, can be produced by a process comprising a step of reacting a compound of formula (II) R-C(O)-O-Ar wherein R and Ar are as defined above with a fluorination agent at a temperature of below +100°C.