174308-13-5Relevant academic research and scientific papers
4-Phenyloxazolidin-2-ones and isoindolin-1-ones: Chiral auxiliaries for Diels-Alder reactions of N-substituted 1,3-dienes
McAlonan,Murphy,Nieuwenhuyzen,Reynolds,Sarma,Stevenso,Thompson
, p. 69 - 79 (2007/10/03)
Terminally N-substituted dienes derived from 3-methylisoindolin-1-one, 4-isopropyl- and 4-phenyloxazolidin-2-one undergo Diels-Alder reaction with a range of activated dienophiles. The reactions reported are completely regio- and endo-selective, with the diastereoisomeric excess with respect to the auxiliary good to excellent in most of the cases reported. A model has been developed for rationalising the stereochemical outcome of these reactions.
Chiral dienamides - Substrates for asymmetric synthesis of amido cyclohexenes
Murphy,Nieuwenhuyzen,Reynolds,Sarma,Stevenson
, p. 9533 - 9536 (2007/10/02)
Chiral dienamides, derived from chiral amines and oxazolidinones, react with electron deficient dienophiles to give amino-cyclohexenes with good to excellent de's.
