174363-71-4

Basic information

• Product Name: Piperidine, 2-(trimethylsilyl)- (9CI)
• Synonyms: Piperidine, 2-(trimethylsilyl)- (9CI)
• CAS NO: 174363-71-4
• Molecular Formula: C₈H₁₉NSi
• Molecular Weight: 157.32866
• Product Categories: SILYL
• Mol File: 174363-71-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Piperidine, 2-(trimethylsilyl)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Piperidine, 2-(trimethylsilyl)- (9CI)(174363-71-4)
• EPA Substance Registry System: Piperidine, 2-(trimethylsilyl)- (9CI)(174363-71-4)

Safety Data

• Hazardous Substances Data: 174363-71-4(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 123387-54-2 N-Boc-2-trimethylsilylpiperidine 
• 75844-69-8 t-butyl piperidinecarboxylate 

Downstream Products

• 491-43-0 5-Methyl-1-azabicyclo<4.4.0>decane 
• 174363-68-9 Octahydro-indolizine-1-carbaldehyde 
• 10159-79-2 lupinine 
• 185305-34-4 (2-Amino-phenyl)-(2-trimethylsilanyl-piperidin-1-yl)-methanone 
• 120153-68-6 N-benzylpiperidine-2-carbonitrile 

Relevant articles and documents

Substituted amino silane compounds and catalyst for the polymerization of alpha-olefins containing them

An aminosilane of the formula: where R1is a linear or branched C1-22alkyl or C3-22cycloalkyl, which may be substituted with at least one halogen atom; R2is a bis(linear or branched C1-22alkyl or C3-22cycloalkyl)amino, a substituted piperidinyl, a substituted pyrrolidinyl, decahydroquinolinyl, 1,2,3,4-tetrahydroquinolinyl or 1,2,3,4-tetrahydroisoquinolinyl, with the substituent selected from the group consisting of C1-8alkyl, phenyl, C1-8linear or branched alkylsubstituted phenyl and trimethylsilyl, with the proviso that when the substituent is C1-8alkyl, there must be at least two such substituent groups present and R1must contain halogen; and R3is a linear or branched C1-8alkyl or C3-8cycloalkyl. The aminosilane may be reacted with an aluminum-alkyl compound and a solid component comprising a titanium compound having at least one titanium-halogen bond and an electron donor, both supported on an activated anhydrous magnesium dihalide, to form a catalyst for polymerization of olefins.

Sequential two-electron oxidation of α,α′-disilylmethylamines to generate non-stabilized azomethine ylide: An ideal approach for the construction of substituted and fused pyrrolidine ring systems

α,α′-Di(trimethylsilylmethyl)amines undergo sequential double desilylation processes, by two-electron oxidation initiated either by photoinduced electron transfer (PET) or Ag(I)F, to produce non-stabilized azomethine ylides efficiently which upon trapping with appropriate dipolarophiles give the corresponding pyrrolidines. Application of this strategy to cyclic analogue for the rapid construction of biologically important 1-azabicyclo[m,3.0]alkane framework is discussed.

Ag(I)F as one electron oxidant for promoting sequential double desilylation : An ideal approach to non-stabilized azomethine ylides for the rapid construction of 1-azabicyclo (m:3:0) alkanes

A novel methodology for effecting sequential double desilylation by Ag(I)F for the generation of non-stabilized azomethine ylide and its application for the synthesis of 1-azabicyclo(m.3.0) alkane systems are described.