123387-54-2Relevant articles and documents
The barrier to enantiomerization and dynamic resolution of N-Boc-2-lithiopiperidine and the effect of TMEDA
Coldham, Iain,Leonori, Daniele,Beng, Timothy K.,Gawley, Robert E.
, p. 5239 - 5241 (2009)
The kinetics of enantiomerization and dynamic thermodynamic resolution (DTR) of N-Boc-2-lithiopiperidine have been measured, revealing significant differences in enthalpy and entropy for these processes and a role for the achiral ligand TMEDA; the racemization and the DTR are catalytic and first order in [TMEDA], and this has implications for asymmetric synthesis with chiral organolithiums.
INDOLIZIDINE AND QUINOLIZIDINE RING FORMATION IN THE SET-PHOTOCHEMISTRY OF α-SILYLAMINES
Hoegy, Susan E.,Mariano, Patrick S.
, p. 8319 - 8322 (1994)
The scope and limitations of indolizidine and quinolizidine ring forming, SET-photoinduced, α-amino radical cyclization reactions were explored.
Dynamic kinetic and kinetic resolution of N-Boc-2-lithiopiperidine
Coldham, Iain,Patel, Jignesh J.,Raimbault, Sophie,Whittaker, David T. E.
, p. 4534 - 4536 (2008/09/16)
Asymmetric substitution of 2-lithiopiperidines can be achieved by dynamic resolution; the organolithium is formed as a racemic mixture by proton abstraction (or tin-lithium exchange) and is resolved in the presence of a chiral ligand. The Royal Society of
