174416-86-5

Upstream product

• 100-39-0 benzyl bromide 
• 2746-25-0 p-Methoxybenzyl bromide 
• 6153-06-6 (E)-3-methylpent-2-en-4-yn-1-ol 
• 824-94-2 p-methoxybenzyl chloride 
• 1187629-72-6 (E)-(5-(4-methoxybenzyloxy)-3-methylpent-3-en-1-ynyl)trimethylsilane 

Downstream Products

• 196600-14-3 (E)-1-[5-(4-methoxybenzyloxy)-3-methylpent-3-en-1-yn-1-yl]-2,5-dimethoxy-3,4,6-trimethylbenzene 
• 174416-87-6 (2R,3R)-1-(4-methoxybenzyloxy)-3-methylpent-4-yne-2,3-diol 
• 910043-10-6 (E)-6-[(4-methoxyphenyl)methoxy]-4-methylhex-4-en-2-yn-1-ol 
• 1187629-73-7 (E)-1-methoxy-4-((3-methylhex-2-en-4-ynyloxy)methyl)benzene 
• 196600-29-0 (2S,3S)-1-(4-methoxybenzyloxy)-5-(2,5-dimethoxy-3,4,6-trimethylphenyl)-3-methylpent-4-yne-2,3-diol 
• 198820-49-4 (4R,5R)-4-ethinyl-5-(4-methoxybenzyloxymethyl)-2,2,4-trimethyl-1,3-dioxolane 
• 202814-85-5 [(4R,5R)-5-(4-Methoxy-benzyloxymethyl)-2,2,4-trimethyl-[1,3]dioxolan-4-ylethynyl]-trimethyl-silane 
• 136786-41-9 tert-Butyl-[(6E,8E,10E)-(2S,4S,5S)-12-(4-methoxy-benzyloxy)-5-methoxymethoxy-2,4,10-trimethyl-dodeca-6,8,10-trienyloxy]-diphenyl-silane 
• 910042-96-5 6-{(1E,3S,5S,6S,7E,9E,11E)-[13-(4-methoxybenzyloxy)-6-(methoxymethoxy)-1,3,5,11-tetramethyltrideca-1,7,9,11-tetraen-1-yl]}-2,2-dimethyl-4H-1,3-dioxen-4-one 
• 910043-30-0 (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trienal 
• 910043-13-9 (2S,4S,5S,6E,8E,10E)-12-(4-methoxybenzyloxy)-5-(methoxymethoxy)-2,4,10-trimethyldodeca-6,8,10-trien-1-ol 
• 910043-09-3 diphenyl[(2E,4E)-6-[(4-methoxyphenyl)methoxy]-4-methylhexa-2,4-dien-1-yl]phosphine oxide 
• 910043-11-7 (2E,4E)-6-[(4-methoxyphenyl)methoxy]-4-methylhexa-2,4-dien-1-ol 
• 910043-12-8 (2E,4E)-1-chloro-6-[(4-methoxyphenyl)methoxy]-4-methylhexa-2,4-diene 

Relevant academic research and scientific papers

Relative stereochemical determination and synthesis of the C1-C17 fragment of a new natural polyketide

(Chemical Equation Presented) The challenging determination of the relative stereochemistry of a complex natural polyketide portion was achieved. After careful NMR analysis, a concise synthesis of a set of possible relative diastereomers (only 6 diastereo

Toward the development of a general chiral auxiliary. A total synthesis of (+)-tetronolide via a tandem ketene-trapping [4 + 2] cycloaddition strategy

A highly convergent, enantioselective total synthesis of the aglycone of the tetrocarcins, (+)-tetronolide, is described. The synthesis highlights the use of several new methods, including camphor auxiliary-directed asymmetric alkylation and the enantiose

Highly selective DNA alkylation at the 5' side G of a 5'GG3' sequence by an aglycon model of pluramycin antibiotics through preferential intercalation into the GG step

Altromycin B and kapurimycin A3 are new members of the pluramycin family antibiotics that alkylate N7 of guanine (G) in duplex DNA at an epoxide subunit attached to the C2 position of the pyranone ring. While 5'AG3' selective alkylation by altr

Enantioselective synthesis of chromans for the preparation of enantiopure vitamin E and analogues

Coupling of the differently protected (hydroxymethyl)enynes 11 a-e and 12a-c with the iodoarene 7 in the presence of catalytic amounts of Pd(PPh3)4 afforded the arylenynes 5a-e and 6a-c which were transformed into the monoprotected chiral trihydroxy compounds 13 a-d and 14a,b by Sharpless bishydroxylation with >95% ee for 13 a-d, 91% ee for 14b, and 64% ee for 14a. A 5-step transformation of 13a led to the desired chroman derivative 3a which was cleaved to give the aldehyde 2 a known precursor for the enantioselective synthesis of vitamin E.