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1745-46-6

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1745-46-6 Usage

General Description

6,11-dihydrodibenzo[b,e]thiepin-11-ol is a chemical compound with the molecular formula C14H14OS. It is a tricyclic antidepressant and a dibenzothiepine derivative that acts as a serotonin-norepinephrine reuptake inhibitor (SNRI). 6,11-DIHYDRODIBENZO(B,E)THIEPIN-11-OL is used for the treatment of major depressive disorder and anxiety disorders, and it is also being investigated for its potential in the treatment of chronic pain. 6,11-dihydrodibenzo[b,e]thiepin-11-ol works by increasing levels of serotonin and norepinephrine in the brain, which can help improve mood and reduce feelings of anxiety. It is available in various forms, such as tablets and capsules, and is typically taken orally as directed by a healthcare professional. Like most medications, it may have side effects and interactions with other drugs, so it is important to use it under proper medical supervision.

Check Digit Verification of cas no

The CAS Registry Mumber 1745-46-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,7,4 and 5 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1745-46:
(6*1)+(5*7)+(4*4)+(3*5)+(2*4)+(1*6)=86
86 % 10 = 6
So 1745-46-6 is a valid CAS Registry Number.

1745-46-6Relevant articles and documents

Pyridazone derivative and its uses

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Paragraph 0163, (2022/01/12)

The present invention belongs to the pharmaceutical field, specifically relates to a pyridazone derivative and its uses, compounds thereof and pharmaceutically acceptable salts, solvates including hydrates, polycrystallines, prodrugs, co-crystallines, tau

Piperazinyl-substituted pyridylalkane, alkene and alkine carboxamides

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Page/Page column 167, (2010/02/11)

The invention relates to new piperazinyl-substituted pyridylalkane, alkene, and alkine acid amides substituted with saturated or one or several-fold unsaturated hydrocarbon residue in the carboxylic acid group according to the general formula (I) as well as methods for the production of these compounds, medicaments containing these and their production as well as their therapeutic use, especially as cytostatic agents and immunosuppressive agents, for example in the treatment or prevention of various types of tumors and control of immune reactions such as autoimmune diseases.

Synthesis and biological activity of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepin derivatives, potential agents for the treatment of cerebrovascular disorders

Kurokawa,Sato,Masuda,Yoshida,Ochi,Zushi,Fujiwara,Naruto,Uno,Matsumoto

, p. 2564 - 2573 (2007/10/02)

A series of 11-[4-(cinnamyl)-1-piperazinyl]-6,11-dihydrodibenz[b,e]oxepins and related compounds were synthesized and evaluated for their protective activities against complete ischemia, normobaric hypoxia, lipidperoxidation and convulsion. Structure-activity relationship studies of this series led to the finding of (E)-1-(3-fluoro-6,11-dihydrodibenz[b,e]oxepin-11-yl)-4-(3-phenyl-2-prop enyl)piperazine dimaleate (50), AJ-3941 with the most appropriate property for combined pharmacological activities. Compound 50 also shows an inhibitory effect against cerebral edema as well when orally given to rats.

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