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7115-91-5

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7115-91-5 Usage

General Description

ETHYL 2-(BROMOMETHYL)BENZOATE is a chemical compound that is commonly used in the synthesis and production of various organic compounds. It is an ester of benzoic acid and ethyl alcohol with a bromomethyl functional group attached to the benzene ring. ETHYL 2-(BROMOMETHYL)BENZOATE is often utilized in organic chemistry as a building block for the synthesis of biologically active molecules, pharmaceuticals, and agrochemicals. It is known for its versatile reactivity and ability to participate in a wide range of organic reactions, making it a valuable component in the manufacturing of various products across different industries. Additionally, it is important to handle this compound with proper safety precautions, as it is a potentially hazardous substance.

Check Digit Verification of cas no

The CAS Registry Mumber 7115-91-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 7,1,1 and 5 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 7115-91:
(6*7)+(5*1)+(4*1)+(3*5)+(2*9)+(1*1)=85
85 % 10 = 5
So 7115-91-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H11BrO2/c1-2-13-10(12)9-6-4-3-5-8(9)7-11/h3-6H,2,7H2,1H3

7115-91-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ETHYL 2-(BROMOMETHYL)BENZOATE

1.2 Other means of identification

Product number -
Other names Ethyl2-(Bromomethyl)benzoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:7115-91-5 SDS

7115-91-5Relevant articles and documents

Metal Complexes with Macrocyclic Ligands Part XXV One-Step Synthesis of Mono-N-substituted Azamacrocycles with a Carboxylic Group in the Side-Chain and their Complexes with Cu2+ and Ni2+

Studer, Martin,Kaden, Thomas A.

, p. 2081 - 2086 (1986)

Mono-N-substituted azamacrocycles 2-7, containing a carboxyalkyl or carboxyaryl side-chain, are obtained by reacting a five-fold excess of the macrocycle with 1 equiv. of a suitable halogenocarboxylic acid in alkaline aqueous EtOH.For halogenocarboxylic a

Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid

Mélin, Léa,Abdullayev, Shuay,Fnaiche, Ahmed,Vu, Victoria,González Suárez, Narjara,Zeng, Hong,Szewczyk, Magdalena M.,Li, Fengling,Senisterra, Guillermo,Allali-Hassani, Abdellah,Chau, Irene,Dong, Aiping,Woo, Simon,Annabi, Borhane,Halabelian, Levon,LaPlante, Steven R.,Vedadi, Masoud,Barsyte-Lovejoy, Dalia,Santhakumar, Vijayaratnam,Gagnon, Alexandre

, p. 2982 - 3002 (2021/08/03)

The YAP-TEAD transcriptional complex is responsible for the expression of genes that regulate cancer cell growth and proliferation. Dysregulation of the Hippo pathway due to overexpression of TEAD has been reported in a wide range of cancers. Inhibition of TEAD represses the expression of associated genes, demonstrating the value of this transcription factor for the development of novel anti-cancer therapies. We report herein the design, synthesis and biological evaluation of LM98, a flufenamic acid analogue. LM98 shows strong affinity to TEAD, inhibits its autopalmitoylation and reduces the YAP-TEAD transcriptional activity. Binding of LM98 to TEAD was supported by 19F-NMR studies while co-crystallization experiments confirmed that LM98 is anchored within the palmitic acid pocket of TEAD. LM98 reduces the expression of CTGF and Cyr61, inhibits MDA-MB-231 breast cancer cell migration and arrests cell cycling in the S phase during cell division.

INFLUENZA VIRUS REPLICATION INHIBITOR AND USES THEREOF

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Paragraph 00258; 00260, (2020/05/21)

The invention belongs to the field of medicine, and particularly relates to a novel compound as a replication inhibitor of influenza virus and a preparation method thereof, a pharmaceutical composition comprising the compound and use of the compound and pharmaceutical composition thereof in treating influenza. The present invention provides a compound having Formula (I) or a stereoisomer, a tautomer, an N-oxide, a solvate, a metabolite, a pharmaceutically acceptable salt or a prodrug thereof, The compound of the present invention can inhibit influenza virus well, and/or has lower cytotoxicity, better in vivo pharmacokinetic properties and in vivo pharmacodynamic properties.

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