17450-30-5 Usage
Description
1-Octadecyl-1H-pyrrole-2,5-dione, commonly known as Nedocromil, is a pyrrole derivative with potent anti-inflammatory properties. It is recognized for its efficacy in stabilizing mast cell membranes and inhibiting the release of histamine and other inflammatory mediators, which are crucial in the pathophysiology of asthma and allergic reactions.
Uses
Used in Pharmaceutical Industry:
1-Octadecyl-1H-pyrrole-2,5-dione is used as an anti-inflammatory agent for the treatment of asthma and allergic conjunctivitis. It functions by stabilizing mast cell membranes, thereby preventing the release of inflammatory substances in response to allergens, which helps in managing and preventing the symptoms associated with these conditions.
Used in Respiratory Therapy:
Nedocromil is used as a bronchodilator and anti-inflammatory in the treatment of asthma. It helps to reduce airway inflammation and constriction, providing relief from asthma symptoms and improving lung function.
Used in Ophthalmic Treatments:
In the form of ophthalmic solutions, 1-octadecyl-1H-pyrrole-2,5-dione is used for the treatment of allergic conjunctivitis. It alleviates the ocular symptoms of allergies, such as itching, redness, and swelling, by reducing the inflammatory response.
Used in Allergy Management:
Nedocromil is utilized as an anti-allergic medication to help control allergic reactions by inhibiting the release of histamine and other mediators, which are responsible for the symptoms of allergies.
Check Digit Verification of cas no
The CAS Registry Mumber 17450-30-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,4,5 and 0 respectively; the second part has 2 digits, 3 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 17450-30:
(7*1)+(6*7)+(5*4)+(4*5)+(3*0)+(2*3)+(1*0)=95
95 % 10 = 5
So 17450-30-5 is a valid CAS Registry Number.
InChI:InChI=1/C22H39NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-23-21(24)18-19-22(23)25/h18-19H,2-17,20H2,1H3
17450-30-5Relevant articles and documents
Drug delivery system
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Page/Page column 6-7, (2008/06/13)
A combination product comprising a positive oil in water emulsion wherein said emulsion comprises a compound presenting free NH2 groups, at its natural state, at the oil-water interface, and an antibody, wherein said compound is linked to said antibody by a heterobifunctional linker, linking said NH2 groups to SH groups on the antibody hinge region.