174522-75-9

Upstream product

• 79378-81-7 4-amino-6-phenyl-7(8H)-pteridinone 
• 21740-23-8 3,5-O-bis(4-chlorobenzoyl)-2-deoxy-α-D-ribofuranosyl chloride 
• 174522-74-8 4-N,N-dimethylaminomethyleneimino-6-phenyl-7(8H)-pteridone 

Downstream Products

• 174522-76-0 4-amino-6-phenyl-8-(2-deoxy-β-D-ribofuranosyl)-pteridine-7-one 
• 174522-77-1 4-Amino-8-{(2R,4S,5R)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-tetrahydro-furan-2-yl}-6-phenyl-8H-pteridin-7-one 

Relevant academic research and scientific papers

A new efficient method in nucleoside synthesis

A new stereo- and regioselective synthesis for adenosine analogous nucleosides is described. Starting from 2- and 6-substituted 4-amino-7(8H)-pteridinones, DBU deprotonation and the ribosylation with an α-haloribofuranose derivative leads to the corresponding pteridine-N-8-β-D-nucleosides in reasonably good yields.